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ecgonine methyl ester biosynthetic process
Known as:
ecgonine methyl ester formation
, ecgonine methyl ester biosynthesis
, ecgonine methyl ester anabolism
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The chemical reactions and pathways resulting in the formation of ecgonine methyl ester. [GOC:TermGenie, PMID:22665766]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
R. Brim
,
Kathleen R. Noon
,
+4 authors
J. Woods
Molecular Pharmacology
2011
Corpus ID: 24225848
Cocaine toxicity is a widespread problem in the United States, responsible for more than 500,000 emergency department visits a…
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Highly Cited
2000
Highly Cited
2000
Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans.
G. Carmona
,
R. Jufer
,
+5 authors
C. Schindler
Drug metabolism and disposition: the biological…
2000
Corpus ID: 17989626
Butyrylcholinesterase (BChE) is known to metabolize cocaine in humans. In the present study, three different experiments were…
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1997
1997
Determination of esterase-catalyzed cocaine metabolite formation by high-performance liquid chromatography with ultraviolet detection.
K. Y. Kim
,
L. Bornheim
Journal of chromatographic science
1997
Corpus ID: 26448260
A reversed-phase high-performance liquid chromatographic (HPLC) method for the determination of cocaine metabolites produced in…
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1995
1995
Lethal Toxicity from Equimolar Infusions of Cocaine and Cocaine Metabolites in Conscious and Anesthetized Rats
B. Mets
,
L. Virág
Anesthesia and analgesia
1995
Corpus ID: 21916209
We compared the lethal toxicity of cocaine with that of three of its metabolites to determine the contribution of these…
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Highly Cited
1993
Highly Cited
1993
Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver.
S. Roberts
,
R. Harbison
,
R. C. James
Drug metabolism and disposition: the biological…
1993
Corpus ID: 23082502
Previous studies have suggested that the esteratic metabolism of cocaine to benzoylecgonine may be inhibited by the presence of…
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1984
1984
In vivo and in vitro studies on cocaine metabolism: ecgonine methyl ester as a major metabolite of cocaine.
K. Matsubara
,
M. Kagawa
,
Y. Fukui
Forensic science international
1984
Corpus ID: 13732010
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