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dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity

Known as: uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity, dolichyl-phosphate N-acetylglucosaminyltransferase activity, dolichyl phosphate N-acetylglucosaminyltransferase activity 
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate. [EC:2.4.1.153]
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
High-resolution mass spectrometry glycoprofiling of intact transferrin for diagnosis and subtype identification in the congenital disorders of glycosylation.
Diagnostic screening of the congenital disorders of glycosylation (CDG) generally involves isoelectric focusing of plasma… Expand
2005
2005
Abnormalities Caused by Carbohydrate Alterations in Iβ6-N-Acetylglucosaminyltransferase-Deficient Mice
ABSTRACT Iβ6-N-acetylglucosaminyltransferase (IGnT) catalyzes the branching of poly-N-acetyllactosamine carbohydrate chains. In… Expand
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2004
2004
ProcessingO-glycan core 1, Galβ1-3GalNAcα-R. Specificities of core 2, UDP-GlcNAc: Galβ1-3GalNAc-R(GlcNAc to GalNAc) β6-N-acetylglucosaminyltransferase and CMP-sialic acid:Galβ1-3GalNAc-R α3…
To elucidate control mechanisms ofO-glycan biosynthesis in leukemia and to develop biosynthetic inhibitors we have characterized… Expand
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2003
2003
Usefulness of the Real-Time Reverse Transcription-Polymerase Chain Reaction Assay Targeted to α1,4-N-Acetylglucosaminyltransferase for the Detection of Gastric Cancer
α1,4-N-acetylglucosaminyltransferase (α4GnT) is a glycosyltransferase that forms a unique glycan, GlcNAcα1 → 4Galβ → R… Expand
1999
1999
Expression of the insulin-like growth factor 1 receptor (IGF-1R) in breast cancer cells: evidence for a regulatory role of dolichyl phosphate in the transition from an intracellular to an…
In this study we provide evidence that the low expression of IGF-1R at the cell surface of estrogen-independent breast cancer… Expand
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1999
1999
Expression and characterization of rat UDP-N-acetylglucosamine: α-3-d-mannoside β-1,2-N-acetylglucosaminyltransferase I in Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is a useful host for the production of heterologous proteins through the secretory pathway… Expand
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1989
1989
Separation into two major forms of beta(1-3)N-acetylglucosaminyltransferase from human serum.
The major beta(1-3)N-acetylglucosaminyltransferase [beta(1-3)GlcNAc-transferase] activity in human serum was isolated by DEAE… Expand
1987
1987
Changes in hepatic dolichol and dolichyl monophosphate caused by treatment of rats with inducers of the endoplasmic reticulum and peroxisomes and during ontogeny.
Rats were treated with various inducers of the endoplasmic reticulum and peroxisomes and the properties and distributions of… Expand
Highly Cited
1976
Highly Cited
1976
Isolation and characterization of two mouse L cell lines resistant to the toxic lectin ricin.
Two variant mouse L cell lines (termed CL 3 and CL 6) have been selected for resistant to ricin, a galactose-binding lectin with… Expand
1975
1975
Glycoprotein biosynthesis: studies on thyroid mannosyltransferases. II. Characterization of a polyisoprenyl mannosyl phosphate and evaluation of its intermediary role in the glycosylation of…
The transfer of mannose from GDP-mannonse to exogenous glycopeptides and simple glycosides has been shown to be carried out by… Expand
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