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dolichol biosynthetic process

Known as: dolichol biosynthesis, dolichol synthesis, dolichol formation 
The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene… 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Insights into complexity of congenital disorders of glycosylation
Biochemical and biological properties of glycoconjugates are strongly determined by the specific structure of its glycan parts… 
Review
2011
Review
2011
From glycosylation disorders to dolichol biosynthesis defects: a new class of metabolic diseases
Polyisoprenoid alcohols are membrane lipids that are present in every cell, conserved from archaea to higher eukaryotes. The most… 
Highly Cited
2008
Highly Cited
2008
Dolichol Biosynthesis and Its Effects on the Unfolded Protein Response and Abiotic Stress Resistance in Arabidopsis[W][OA]
Dolichols are long-chain unsaturated polyisoprenoids with multiple cellular functions, such as serving as lipid carriers of… 
Highly Cited
2001
Highly Cited
2001
Yeast Saccharomyces cerevisiae has two cis‐prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis
Background Dolichol is a family of long‐chain polyprenols, which is utilized as a sugar carrier in protein glycosylation in the… 
Highly Cited
2000
Highly Cited
2000
Characterization of dehydrodolichyl diphosphate synthase of Arabidopsis thaliana, a key enzyme in dolichol biosynthesis
Highly Cited
1999
Highly Cited
1999
The Yeast RER2 Gene, Identified by Endoplasmic Reticulum Protein Localization Mutations, Encodescis-Prenyltransferase, a Key Enzyme in Dolichol Synthesis
ABSTRACT As an approach to understand the molecular mechanisms of endoplasmic reticulum (ER) protein sorting, we have isolated… 
Highly Cited
1999
Highly Cited
1999
The Escherichia coli Homologue of Yeast Rer2, a Key Enzyme of Dolichol Synthesis, Is Essential for Carrier Lipid Formation in Bacterial Cell Wall Synthesis
ABSTRACT We found in the Escherichia coli genome sequence a homologue of RER2, a Saccharomyces cerevisiaegene required for proper… 
Highly Cited
1987
Highly Cited
1987
In vitro and in vivo synthesis of dolichol and other main mevalonate products in various organs of the rat.
The relative rate of biosynthesis of dolichol from [3H]mevalonate in nine rat organs was studied in slices and in the whole… 
1981
1981
Sequential cycles of cholesterol and dolichol synthesis in mouse spleens during phenylhydrazine-induced erythropoiesis.
Highly Cited
1979
Highly Cited
1979
Inter-relationships between dolichol and sterol synthesis in mammalian cell cultures.
A method is described for the measurement of [‘“Clacetate incorporation into dolichol in cultured mammalian cells. In various… 
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