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dolichol biosynthetic process

Known as: dolichol biosynthesis, dolichol synthesis, dolichol formation 
The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene… Expand
National Institutes of Health

Papers overview

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2015
2015
A two-component enzyme complex is required for dolichol biosynthesis in tomato.
Dolichol plays an indispensable role in the N-glycosylation of eukaryotic proteins. As proteins enter the secretory pathway they… Expand
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2014
2014
High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation[S]
Accurate protein inventories are essential for understanding an organelle's functions. The lipid droplet (LD) is a ubiquitous… Expand
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2011
2011
Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation.
Dolichol monophosphate (Dol-P) functions as an obligate glycosyl carrier lipid in protein glycosylation reactions. Dol-P is… Expand
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Highly Cited
2008
Highly Cited
2008
Dolichol biosynthesis and its effects on the unfolded protein response and abiotic stress resistance in Arabidopsis.
Dolichols are long-chain unsaturated polyisoprenoids with multiple cellular functions, such as serving as lipid carriers of… Expand
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2003
2003
Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans.
The sterol pathway in Candida albicans is the target for several classes of antifungal drugs. Intermediates in the sterol pathway… Expand
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2001
2001
Yeast Saccharomyces cerevisiae has two cis-prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis.
BACKGROUND Dolichol is a family of long-chain polyprenols, which is utilized as a sugar carrier in protein glycosylation in the… Expand
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2000
2000
Characterization of dehydrodolichyl diphosphate synthase of Arabidopsis thaliana, a key enzyme in dolichol biosynthesis.
The enzyme dehydrodolichyl diphosphate (dedol-PP) synthase is a cis-prenyltransferase that catalyzes the synthesis of dedol-PP… Expand
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2000
2000
Identification, purification and characterization of an acetoacetyl-CoA thiolase from rat liver peroxisomes.
Acetoacetyl-CoA specific thiolases catalyse the cleavage of acetoacetyl-CoA into two molecules of acetyl-CoA and the synthesis… Expand
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Highly Cited
1999
Highly Cited
1999
The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis.
As an approach to understand the molecular mechanisms of endoplasmic reticulum (ER) protein sorting, we have isolated yeast rer… Expand
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1999
1999
The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis.
We found in the Escherichia coli genome sequence a homologue of RER2, a Saccharomyces cerevisiae gene required for proper… Expand
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