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disorazole C1

National Institutes of Health

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2 relations

Broader (2)

MacrolidesOxazoles

Papers overview

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2009
2009
Microtubule Binding and Disruption and Induction of Premature Senescence by Disorazole C1
Disorazoles comprise a family of 29 macrocyclic polyketides isolated from the fermentation broth of the myxobacterium Sorangium… 
2007
2007
Disorazole C1: A potent antimitotic agent that induces premature senescence
1219 Disorazole C 1 is a potent, cytotoxic natural product, with IC 50 values of 1 disrupted microtubules in cells as early as 24… 
2003
2003
Polynucleotides codant la synthase de polycetide disorazole
L'invention concerne des domaines de la synthase de polycetide disorazole et des polynucleotides les codant. L'invention concerne… 
2001
2001
Studies on the total synthesis of disorazole C1. An advanced macrocycle intermediate.
Synthesis of protected tetradehydro-(6,6'-S)-(14,14'-S)-(16,16'-R)-disorazole (3), a potential precursor to the natural product… 
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