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dirithromycin

Known as: Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-,(9S(R))-, dirithromycin [Chemical/Ingredient] 
A semi-synthetic macrolide antibiotic pro-drug. Dirithromycin is converted by hydrolysis during intestinal absorption into the microbiologically… Expand
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
ABSTRACT The susceptibilities of Mycoplasma hominis,Mycoplasma pneumoniae, and Ureaplasma urealyticum to eight new antimicrobial… Expand
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Highly Cited
1999
Highly Cited
1999
The potential of 14/15 membered macrolides to cause phospholipidosis has been prospectively assessed, and structure-effects… Expand
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1998
1998
We evaluated a human monocyte cell line (HL-60) as a model for testing the intracellular activity of anti-Legionella antibiotics… Expand
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Highly Cited
1998
Highly Cited
1998
  • P. Edelstein
  • Annals of Internal Medicine
  • 1998
  • Corpus ID: 9125626
Erythromycin became the de facto standard of treatment for Legionnaires disease soon after the first recognized epidemic of this… Expand
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Highly Cited
1996
Highly Cited
1996
The calculation of pharmacokinetic/pharmacodynamic surrogates from concentrations in serum has been shown to yield important… Expand
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Review
1995
Review
1995
SummaryMacrolide antibiotics can interact adversely with commonly used drugs, usually by altering metabolism due to complex… Expand
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Review
1993
Review
1993
After the discovery of erythromycin and other natural compounds, including oleandomycin, spiramycin, josamycin and midecamycin… Expand
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1993
1993
  • A. Bauernfeind
  • The Journal of antimicrobial chemotherapy
  • 1993
  • Corpus ID: 11330808
Improvements with regard to the in-vitro activity of new macrolides are marginal and apply mainly to Haemophilus spp., Moraxella… Expand
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Review
1992
Review
1992
SummaryThe macrolide antibiotics include natural members, prodrugs and semisynthetic derivatives. These drugs are indicated in a… Expand
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Highly Cited
1988
Highly Cited
1988
The in vitro activities of several 14-, 15- and 16-membered macrolides were compared with that of erythromycin. In general, 14… Expand
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