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dirithromycin

Known as: Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-,(9S(R))-, dirithromycin [Chemical/Ingredient] 
A semi-synthetic macrolide antibiotic pro-drug. Dirithromycin is converted by hydrolysis during intestinal absorption into the microbiologically… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (2)

Anti-Bacterial AgentsErythromycin
BronchitisCommunity-Acquired InfectionsDecreased Protein Synthesis [PE]Haemophilus Infections

Narrower (2)

LY 237216Nortron

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Comparison of dirithromycin and penicillin for treatment of streptococcal pharyngitis
In the treatment of group A beta-hemolytic streptococcal pharyngitis, penicillin is the drug of choice and erythromycin is the… 
1995
1995
Macrolides resistance of common bacteria isolated from Taiwan.
1995
1995
A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis.
The safety and efficacy of dirithromycin and clarithromycin were compared in a single-blind, multicentre study of patients with… 
1993
1993
Clinical efficacy of dirithromycin in pneumonia.
In a double-blind, double-dummy, multicentre study the efficacy and safety of dirithromycin 500 mg/day given orally once daily… 
1993
1993
Dirithromycin in the treatment of skin and skin structure infections.
The efficacy and safety of dirithromycin were compared with those of erythromycin or miocamycin for the treatment of skin and/or… 
1993
1993
Tissue distribution of dirithromycin: comparison with erythromycin.
In order to ensure effective in-vivo activity, high antibiotic concentrations need to be achieved rapidly at the site of the… 
Review
1993
Review
1993
Safety profile of dirithromycin.
Dirithromycin is a recently developed oral antibiotic, and has been shown to be effective in the treatment of respiratory tract… 
1992
1992
In-vitro activities of 14-, 15- and 16-membered macrolides against gram-positive cocci.
The in-vitro activities of the 14-membered macrolides erythromycin, dirithromycin, roxithromycin, clarithromycin, the 15-membered… 
1992
1992
Investigation of the in-vitro uptake, intraphagocytic biological activity and effects on neutrophil superoxide generation of dirithromycin compared with erythromycin.
The cellular uptake by human neutrophils and the intraphagocytic biological activity of the new macrolide antimicrobial agent… 
Highly Cited
1991
Highly Cited
1991
Comparative activity of macrolides against Toxoplasma gondii demonstrating utility of an in vitro microassay
The utility of spiramycin for preventing transplacental transmission of toxoplasmosis and the efficacy of conventional macrolides… 
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