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diosgenone

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2014
01219852014

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2 relations

Broader (2)

Spiro CompoundsTriterpenes

Related mentions per year

Related mentions per year

1949-2018
19401960198020002020
diosgenone
Triterpenes
Spiro Compounds

Papers overview

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2014
2014
Partial characterization of Plasmodium falciparum trophozoite proteome under treatment with quinine, mefloquine and the natural antiplasmodial diosgenone.
INTRODUCTION Despite efforts to control malaria, around 10% of the world population is at risk of acquiring this disease… (More)
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Review
2013
Review
2013
Diosgenone synthesis, anti-malarial activity and QSAR of analogues of this natural product.
Solanum nudum Dunal steroids have been reported as being antimalarial compounds; however, their concentration in plants is low… (More)
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2012
2012
Diosgenone: a second P21 polymorph
Diosgenone [(20S,22R,25R)-spirost-4-en-3-one, C(27)H(40)O(3)] has been proposed as a new therapeutic alternative for the… (More)
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2009
2009
Characterization of P450 FcpC, the enzyme responsible for bioconversion of diosgenone to isonuatigenone in Streptomyces virginiae IBL-14.
A new cytochrome P450 monooxygenase, FcpC, from Streptomyces virginiae IBL-14 has been identified. This enzyme is found to be… (More)
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2009
2009
Effect of Solanum nudum steroids on uninfected and Plasmodium falciparum-infected erythrocytes.
Steroids from Solanum nudum (SNs) have demonstrated antiplasmodial activity against erythrocytic stages of the Plasmodium… (More)
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2007
2007
Biotransformation of diosgenin to nuatigenin-type steroid by a newly isolated strain, Streptomyces virginiae IBL-14
An actinomycete strain IBL-14 isolated from soil by utilizing diosgenin as the sole carbon and energy source was identified as… (More)
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2004
2004
Evaluation of clastogenic potential of the antimalarial plant Solanum nudum.
Compounds isolated from Solanum nudum have shown in vitro antimalarial activity against the FCB-2 strain of Plasmodium falciparum… (More)
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2003
2003
Evaluation of the mutagenicity of antimalarial products isolated from Solanum nudum (Solanaceae).
Diosgenone is a major component of the hexane extract from the plant Solanum nudum (Solanaceae). The products from degraded and… (More)
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2002
2002
Low temperature crystal structure of natural diosgenone.
The molecular structure of diosgenone, a natural steroidal sapogenin, closely related to diosgenin and isolated from Solanum… (More)
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1985
1985
The use of a hydrophobic resin as a product reservoir in steroid transformations.
Particles of the hydrophobic resin polydimethylsiloxane were found to preferentially accumulate steriods on the basis of their… (More)
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