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diosgenone

National Institutes of Health

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Spiro CompoundsTriterpenes

Papers overview

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2020
2020
Biocatalytic allylic hydroxylation of unsaturated triterpenes and steroids by Bacillus megaterium CGMCC 1.1741.
2014
2014
Simultaneous quantification of antimalarial steroids in solanum nudum extracts by high performance liquid chromatography (hplc)
Los esteroides con reconocida actividad antiplasmodica aislados de las hojas de Solanum nudum, fueron cuantificados en extractos… 
2012
2012
Diosgenone: a second P21 polymorph
Diosgenone [(20S,22R,25R)-spirost-4-en-3-one, C27H40O3] has been proposed as a new therapeutic alternative for the treatment of… 
2009
2009
Plasmodium falciparum: effect of Solanum nudum steroids on thiol contents and beta-hematin formation in parasitized erythrocytes.
2009
2009
Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14
ABSTRACT A new cytochrome P450 monooxygenase, FcpC, from Streptomyces virginiae IBL-14 has been identified. This enzyme is found… 
2003
2003
Evaluation of the mutagenicity of antimalarial products isolated from Solanum nudum (Solanaceae).
Diosgenone is a major component of the hexane extract from the plant Solanum nudum (Solanaceae). The products from degraded and… 
2002
2002
Low Temperature Crystal Structure of Natural Diosgenone
The molecular structure of diosgenone, a natural steroidal sapogenin, closely related to diosgenin and isolated from Solanum… 
2001
2001
Effect of Solanum nudum extracts on the liver of mice infected with Plasmodium berghei.
The plant Solanum nudum has been used by the community of Tumaco (Nariño, Colombia) as a cure for malaria. Our group has… 
2001
2001
Apertura del anillo F de la Diosgenona y actividad Antimalárica in vitro de los productos de reacción
Treatment of sapogenine diosgenone (compound .1) in a sealed tube with acetic anhidride, at 200°C for 6 hours, led to obtention… 
1985
1985
The use of a hydrophobic resin as a product reservoir in steroid transformations
Particles of the hydrophobic resin polydimethylsiloxane were found to preferentially accumulate steriods on the basis of their… 
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