dihydrotamoxifen

Known as: 1-(4-(2-(dimethylamino)ethoxy)phenyl)-1,2-diphenylbutane

National Institutes of Health

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1987

1987

Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).

As part of a study into nonisomerizable antiestrogens, the diastereoisomeric dihydrotamoxifens 7 and 8 were prepared by catalytic…