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dihydroeptastatin
Known as:
7-(1-((1S,2S,4aR,6R,8S,8aS)-6-hydroxy-8-((2(S)-methyl-1-oxobutyl)oxy)-1,2,4a,5,6,7,8,8a-octahydro-2-methylnaphthalenyl))-3(R),5(R)-dihydroxyheptanoate
National Institutes of Health
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2 relations
Broader (1)
Pravastatin
analogs & derivatives
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1992
1992
Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Elisabeth A. Bone
,
Alan H. Davidson
,
Christopher Lewis
,
Richard S. Todd
Journal of Medicinal Chemistry
1992
Corpus ID: 32897362
The total synthesis of the novel hydroxylated HMG-CoA reductase inhibitor dihydroeptastatin (7) is described. The key C-3…
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