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dihomo-prostaglandin I(2)

Known as: dihomo-PGI(2) 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Epoprostenol
analogs & derivatives

Papers overview

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Review
2012
Review
2012
Molecular Mechanisms Regulating the Vascular Prostacyclin Pathways and Their Adaptation during Pregnancy and in the Newborn
Prostacyclin (PGI2) is a member of the prostanoid group of eicosanoids that regulate homeostasis, hemostasis, smooth muscle… 
2012
2012
Effects of Celecoxib on Prostanoid Biosynthesis and Circulating Angiogenesis Proteins in Familial Adenomatous Polyposis
Vascular cyclooxygenase (COX)-2-dependent prostacyclin (PGI2) may affect angiogenesis by preventing endothelial activation and… 
Review
2010
Review
2010
Prostacyclin in vascular diseases. - Recent insights and future perspectives -.
Prostacyclin (PGI(2)) is one of the important vascular prostanoids, the effects of which counteract those of thromboxane (TXA(2… 
2010
2010
Endothelin-1 (ET-1) Increases the Expression of Remodeling Genes in Vascular Smooth Muscle through Linked Calcium and cAMP Pathways
Several important genes that are involved in inflammation and tissue remodeling are switched on by virtue of CRE response… 
Highly Cited
2006
Highly Cited
2006
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function.
We investigated the mechanisms by which inhibitors of prostaglandin G/H synthase-2 (PGHS-2; known colloquially as COX-2) increase… 
Highly Cited
2005
Highly Cited
2005
Sphingosine 1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells
Sphingosine 1-phosphate (S1P) has been shown to exert a variety of biological responses through extracellular specific receptors… 
2004
2004
Signaling through the Prostaglandin I2 Receptor IP Protects against Respiratory Syncytial Virus-Induced Illness
ABSTRACT The role of prostanoids in modulating respiratory syncytial virus (RSV) infection is unknown. We found that RSV… 
Highly Cited
2001
Highly Cited
2001
The Regulation of Uncoupling Protein-2 Gene Expression by ω-6 Polyunsaturated Fatty Acids in Human Skeletal Muscle Cells Involves Multiple Pathways, Including the Nuclear Receptor Peroxisome…
Fatty acids have been postulated to regulate uncoupling protein (UCP) gene expression in skeletal musclein vivo. We have… 
Highly Cited
2000
Highly Cited
2000
Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange.
Aerosolized prostacyclin (PGI(2)) has been suggested for selective pulmonary vasodilation, but its effect rapidly levels off… 
2000
2000
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the…
Having developed a non-insulin-dependent diabetes mellitus (NIDDM) syndrome model in the rabbit using Wirsung duct ligation, it… 
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