dictyodendrin B
National Institutes of Health
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We report a regioselective direct arylation of indoles at the C7 position with (hetero)aryl bromides. The indole scaffold will…
A sequential CH functionalization strategy for the synthesis of the marine alkaloid dictyodendrin B is reported. Our synthesis…
alkaloids known to possess inhibitory activity against telomerase. As telomerase is expressed in most tumor cell lines and its…
The core structure of the telomerase inhibitor, dictyodendrin B, was synthesized by using the palladium-catalyzed cross-coupling…
Concise and flexible total syntheses of the pyrrolo[2,3-c]carbazole alkaloids dictyodendrin B (2), C (3), and E (5) are described…
A concise total synthesis of dictyodendrin B (1) is reported, a scarce marine alkaloid endowed with promising telomerase…