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dichloromethane dehalogenase

 
National Institutes of Health

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Lyase

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Review
2005
Review
2005
Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities.
Bacterial dehalogenases catalyse the cleavage of carbon-halogen bonds, which is a key step in aerobic mineralization pathways of… Expand
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2003
2003
Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11.
The glutathione (GSH)-dependent dichloromethane dehalogenase from Methylophilus sp. strain DM11 catalyzes the dechlorination of… Expand
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2001
2001
Dehalogenation of dichloromethane by dichloromethane dehalogenase/glutathione S-transferase leads to formation of DNA adducts.
Formation of DNA adducts following conversion of dichloromethane by bacterial dichloromethane dehalogenase/glutathione S… Expand
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1998
1998
Effects of Bacterial Host and Dichloromethane Dehalogenase on the Competitiveness of Methylotrophic Bacteria Growing with Dichloromethane
ABSTRACT Methylobacterium sp. strain DM4 andMethylophilus sp. strain DM11 can grow with dichloromethane (DCM) as the sole source… Expand
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Review
1998
Review
1998
Microbial dehalogenases: enzymes recruited to convert xenobiotic substrates.
Microbial dehalogenases are involved in the biodegradation of many important chlorinated pollutants. Some recent studies of… Expand
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1996
1996
Protein engineering studies of dichloromethane dehalogenase/glutathione S-transferase from Methylophilus sp. strain DM11. Ser12 but not Tyr6 is required for enzyme activity.
The structural gene for dichloromethane dehalogenase/glutathione S-transferase (GST, EC 2.5.1.18) from Methylophilus sp. strain… Expand
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1994
1994
Reaction of rat liver glutathione S-transferases and bacterial dichloromethane dehalogenase with dihalomethanes.
Dichloromethane dehalogenase from Methylophilus sp. DM11 is a glutathione S-transferase homolog that is specifically active with… Expand
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Highly Cited
1991
Highly Cited
1991
Theta, a new class of glutathione transferases purified from rat and man.
Glutathione transferases (GSTs) of a novel class, which it is proposed to term Theta, were purified from rat and human liver. Two… Expand
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Highly Cited
1990
Highly Cited
1990
Sequence analysis and expression of the bacterial dichloromethane dehalogenase structural gene, a member of the glutathione S-transferase supergene family.
The nucleotide sequence of a cloned 2.8-kilobase-pair BamHI-PstI fragment containing dcmA, the dichloromethane dehalogenase… Expand
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1986
1986
Evidence for identical dichloromethane dehalogenases in different methylotrophic bacteria.
SUMMARY: The dichloromethane dehalogenases of four facultative methylotrophs that mineralize dichloromethane were compared… Expand
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