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dexefaroxan

National Institutes of Health

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3 relations

Broader (2)

BenzopyransImidazoles

Narrower (1)

RX 831003

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Alteration of olfactory perceptual learning and its cellular basis in aged mice
2007
2007
Noradrenergic control of odor recognition in a nonassociative olfactory learning task in the mouse.
The present study examined the influence of pharmacological modulations of the locus coeruleus noradrenergic system on odor… 
2005
2005
Activation of noradrenergic transmission by α2-adrenoceptor antagonists counteracts deafferentation-induced neuronal death and cell proliferation in the adult mouse olfactory bulb
Highly Cited
2003
Highly Cited
2003
Effects of the α2-adrenoreceptor antagonist dexefaroxan on neurogenesis in the olfactory bulb of the adult rat in vivo: selective protection against neuronal death
2003
2003
Stimulation of postsynaptic alpha1b- and alpha2-adrenergic receptors amplifies dopamine-mediated locomotor activity in both rats and mice.
Recent experiments have shown that mice lacking the alpha1b-adrenergic receptor (alpha1b-AR KO) are less responsive to the… 
2003
2003
Dissimilar Pharmacological Responses by a New Series of Imidazoline Derivatives at Precoupled and Ligand-Activated α2A-Adrenoceptor States: Evidence for Effector Pathway-Dependent Differential…
Whereas agonist-directed differential signaling at a single receptor subtype has become an accepted pharmacological concept… 
2001
2001
Analysis of ligand activation of α2-adrenoceptor subtypes under conditions of equal Gα protein stoichiometry
Abstract. Variations in the measurement of ligand's intrinsic activity between receptor subtypes is a common consequence of… 
2000
2000
Facilitation of constitutive alpha(2A)-adrenoceptor activity by both single amino acid mutation (Thr(373)Lys) and g(alphao) protein coexpression: evidence for inverse agonism.
The recombinant human alpha(2A)-adrenoceptor (alpha(2A)-AR, RC 2.1. ADR.A2A) can be transformed into a constitutively activated… 
2000
2000
Partial to complete antagonism by putative antagonists at the wild‐type α2C‐adrenoceptor based on kinetic analyses of agonist : antagonist interactions
Activation of the recombinant human α2C‐adrenoceptor (α2C AR) by (−)‐adrenaline in CHO‐K1 cells transiently co‐expressing a… 
1999
1999
G‐protein activation by putative antagonists at mutant Thr373Lys α2A adrenergic receptors
Replacement of a threonine by a lysine at position 373 in the C‐terminal portion of the third intracellular loop of the human α2A… 
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