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detorubicin

Known as: Diethoxy-,2-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)-2-oxoethyl ester,(2S-cis) Acetic Acid, 14-diethoxyacetoxydaunorubicin, detrorubicin 
A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with… 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
  • J. Sørensen
  • The clinical respiratory journal
  • 2008
  • Corpus ID: 24456987
Objectives:  The aim of this study was to provide an overview of the most active single agents and combination regimens in… 
Review
1996
Review
1996
  • S. Ong, N. Vogelzang
  • Journal of clinical oncology : official journal…
  • 1996
  • Corpus ID: 24476215
PURPOSE AND DESIGN We reviewed the published literature of clinical studies in malignant pleural mesothelioma, including phase II… 
Review
1988
Review
1988
The treatment of patients with metastatic melanoma remains a difficult problem. It is clear that more effective agents need to be… 
1985
1985
Between January 1981 and December 1983, a prospective therapeutic trial of detorubicin (14‐diethoxyacetoxy‐daunorubicin [DTR… 
1982
1982
51 patients with malignant melanomas who had not previously received chemotherapy were studied in a phase III trial. They were… 
Highly Cited
1980
Highly Cited
1980
Six anthracycline antibiotics with demonstrated antitumor activity in human or experimental tumor systems were studied. The… 
Highly Cited
1979
Highly Cited
1979
Golden hamsters received Adriamycin (ADR), detorubicin (DTR), AD-32, or aclacinomycin (ACM) three times weekly at doses… 
1979
1979
The anthracycline derivatives are intercalating drugs which are of major importance in the treatment of leukemias and in the… 
1979
1979
We have studied the stability, pharmacology, toxicology, and therapeutic activity in mice of detorubicin, a new semisynthetic…