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detorubicin

Known as: Diethoxy-,2-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)-2-oxoethyl ester,(2S-cis) Acetic Acid, 14-diethoxyacetoxydaunorubicin, detrorubicin 
A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

33921 RP

Broader (1)

Daunorubicin
analogs & derivatives

Papers overview

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1987
1987
Activity of (7) anthracycline related compounds in an doxorubicin sensitive human small cell lung cancer line and its doxorubicin resistant descendant. Activity of doxorubicin, daunorubicin, 4…
1980
1980
Ultrastructural study of the cardiotoxicity and light-microscopic findings of the skin after treatment of golden hamsters with seven different anthracyclines.
Golden hamsters were administered seven anthracyclines: adriamycin (ADM), detorubicin (DTR), daunorubicin (DNR), 4'-epi… 
1980
1980
Experimental and clinical activity of a new anthracycline derivative: detorubicin (14-diethoxyacetoxydaunorubicin).
This report concerns the experimental activity and the preliminary clinical results obtained with detorubicin, an anthracycline… 
1980
1980
Clinical study of detorubicin. EORTC Clinical Screening Group.
  • Recent results in cancer research. Fortschritte…
  • 1980
  • Corpus ID: 20604822
A phase II trial of detorubicin (DTR) has been conducted on 164 patients with solid tumors. Regressions greater than or equal to… 
1980
1980
Preliminary results of a phase II trial on solid tumors of detorubicin, a new anthracyclin.
A phase II trial of detorubicin (DTR) has been conducted on 164 patinets with solid tumors. Regressions greater than or equal to… 
1980
1980
Clinical Study of Detorubicin
1979
1979
Clinical activity of detorubicin: a new anthracycline derivative.
The anthracycline derivatives are intercalating drugs which are of major importance in the treatment of leukemias and in the… 
1979
1979
[Ultrastructural study of cardiotoxicity and skin alterations in the golden hamster after treatment with 8 different anthracyclines].
Golden hamsters were submitted to i.p. administration during 4 weeks of 8 anthracyclines, adriamycin (ADM), detorubicin (DTR… 
1979
1979
[Detorubicin (33 921 R.P.): medullary tolerance (author's transl)].
1978
1978
Preliminary results of a phase II trial of aclacinomycin in acute leukaemia and lymphosarcoma
SummaryA phase II trial of which preliminary results are available for 22 patients indicates that aclacinomycin applied in a…