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desmethylmaprotiline

Known as: 9,10-ethanoanthracene-9(10H)-propylamine 
National Institutes of Health

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Maprotiline
analogs & derivatives

Papers overview

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2002
2002
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis.
We describe an analytical procedure for the simultaneous quantification of citalopram (seropram), clozapine (leponex), fluoxetine… 
2002
2002
Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.
From case reports of patients treated with the tetracyclic antidepressant drug maprotiline, it appears that this drug is subject… 
1994
1994
Assay for maprotiline in human serum with improved sensitivity and selectivity.
1992
1992
Pharmacokinetic analysis of maprotiline and its demethylated metabolite in serum and brain of rats after acute and chronic oral administration of maprotiline.
Compartmental model analysis by simultaneous curve fitting was used to ascertain the pharmacokinetic relationship between… 
1990
1990
Pharmacokinetics of maprotiline and its demethylated metabolite in serum and specific brain regions of rats after acute and chronic administration of maprotiline.
The concentrations of maprotiline (MAP) and its demethylated metabolite desmethylmaprotiline (DMAP) in the serum and specific… 
1987
1987
Serum Levels of Maprotiline and Its Adverse Effects on Depressed Patients
Abstract: The relationships between the side effects of maprotiline (MPT) andthe serum concentration of MPT and… 
1987
1987
A Comparison of Maprotiline and Its Desmethylated Metabolite Serum Concentrations in Outpatients and Inpatients
Abstract: An investigation was conducted on drug defaulting in 26 depressed patients (11 outpatients and 15 inpatients) treated… 
1987
1987
[The concentrations of amitriptyline, maprotiline and their demethylated metabolites, nortriptyline and desmethylmaprotiline, in rat plasma and brain].
1980
1980
Relationship Between Blood Concentrations and Clinical Effects of a New Antidepressant “Maprotiline”
Abstract: In conducting the double‐blind controlled study of antidepressants, observations were carried out on the relationship… 
1977
1977
Estimation of maprotiline in serum by gas-chromatography, with use of a nitrogen-specific detector.
We describe a gas-chromatographic procedure for estimating therapeutic concentrations of maprotiline, a new tetracyclic… 
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