Maprotiline

Known as: 9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-, Maprotylina, Dibencycladine 
A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side… (More)
National Institutes of Health

Related topics

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30 relations

Broader (5)

Adrenergic Uptake InhibitorsAntidepressive AgentsAntidepressive Agents, Second-GenerationPolycyclic Hydrocarbons
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BulimiaCocaine-Related DisordersDepressive disorderDrug Allergy
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Narrower (5)

LudiomilMaprotiline Mesylatedesmethylmaprotilinehydroxymaprotilin
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Papers overview

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Highly Cited
2005
Highly Cited
2005
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Huntington's disease (HD) is caused by polyglutamine expansion (exp) in huntingtin. Here, we used a yeast artificial chromosome… (More)
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Highly Cited
2003
Highly Cited
2003
Bi-phasic change in BDNF gene expression following antidepressant drug treatment
The gene for brain derived neurotrophic factor (BDNF) has recently received attention in relation to the therapeutic action of… (More)
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2001
2001
Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: a double-blind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile
BACKGROUND Depression has emerged as a contrastive area of gender differences in psychiatry, as epidemiological data has… (More)
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Highly Cited
1998
Highly Cited
1998
SSRIS versus tricyclic antidepressants in depressed inpatients: a meta-analysis of efficacy and tolerability.
A meta-analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) against nonselective and… (More)
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Highly Cited
1995
Highly Cited
1995
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
This study demonstrated that distinct patterns of active behaviors are produced by antidepressants that selectively inhibit… (More)
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1995
1995
The Serotonin Reuptake Inhibitor Paroxetin Is Superior to the Noradrenaline Reuptake Inhibitor Maprotiline in the Treatment of Premenstrual Syndrome
Recent studies indicate that antidepressant drugs with potent serotonin reuptake inhibiting properties are effective in reducing… (More)
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Highly Cited
1992
Highly Cited
1992
Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline
Chronic exposure to mild unpredictable stress has previously been found to depress the consumption of palatable sweet solutions… (More)
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1992
1992
Antidepressants and cognition: comparative effects of moclobemide, viloxazine and maprotiline
The respective effects of three antidepressant drugs (moclobemide, 450 mg/j; viloxazine, 300 mg/j; maprotiline, 150 mg/j) on… (More)
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1987
1987
Effect of chlorimipramine and maprotiline on experimental anxiety in humans.
In order to assess the role played by serotonin (5-HT) and noradrenaline in anxiety, four groups of healthy volunteers were given… (More)
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1983
1983
Mianserin, maprotiline and intracardiac conduction.
1 High speed surface electrocardiograms were recorded in 35 patients during the baseline and after four weeks' treatment in a… (More)
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