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Maprotiline

Known as: 9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-, Maprotylina, Dibencycladine 
A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side… Expand
National Institutes of Health

Related topics

Related topics

32 relations

Broader (5)

Adrenergic Uptake InhibitorsAntidepressive AgentsAntidepressive Agents, Second-GenerationPolycyclic Hydrocarbons
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BulimiaCocaine-Related DisordersDepressive disorderDrug Allergy
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Narrower (6)

LudiomilMaprotilin HolstenMaprotiline Mesylatedesmethylmaprotiline
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
This method describes the simultaneous determination of amisulpride, amitriptyline, aripiprazole, benperidol, chlorpromazine… Expand
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Highly Cited
2005
Highly Cited
2005
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
This study demonstrated that distinct patterns of active behaviors are produced by antidepressants that selectively inhibit… Expand
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Highly Cited
2005
Highly Cited
2005
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Huntington's disease (HD) is caused by polyglutamine expansion (exp) in huntingtin. Here, we used a yeast artificial chromosome… Expand
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Highly Cited
2005
Highly Cited
2005
Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline
Chronic exposure to mild unpredictable stress has previously been found to depress the consumption of palatable sweet solutions… Expand
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Highly Cited
1998
Highly Cited
1998
Listening to Prozac but Hearing Placebo: A Meta-Analysis of Antidepressant Medication
Mean effect sizes for changes in depression were calculated for 2,318 patients who had been randomly assigned to either… Expand
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Highly Cited
1998
Highly Cited
1998
SSRIs versus tricyclic antidepressants in depressed inpatients: A meta‐analysis of efficacy and tolerability
  • I. Anderson
  • Depression and anxiety
  • 1998
    • Corpus ID: 25730459
A meta‐analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) against nonselective and… Expand
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Highly Cited
1996
Highly Cited
1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
BACKGROUND AND PURPOSE In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from… Expand
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Highly Cited
1995
Highly Cited
1995
The Serotonin Reuptake Inhibitor Paroxetin Is Superior to the Noradrenaline Reuptake Inhibitor Maprotiline in the Treatment of Premenstrual Syndrome
Recent studies indicate that antidepressant drugs with potent serotonin reuptake inhibiting properties are effective in reducing… Expand
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Highly Cited
1992
Highly Cited
1992
Amitriptyline versus maprotiline in postherpetic neuralgia: a randomized, double-blind, crossover trial
&NA; Amitriptyline (AT) relieves some patients with postherpetic neuralgia (PHN). Many patients suffer side effects and better… Expand
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Highly Cited
1988
Highly Cited
1988
Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder: A double-blind comparative study with fluvoxamine and maprotiline.
A double-blind comparative study with fluvoxamine, a specific serotonin uptake inhibitor. and maprotiline, a specific… Expand
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