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desmethylclobazam

National Institutes of Health

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Benzodiazepines

Papers overview

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2018
2018
Effect of Pharmaceutical Formulation of Purified Cannabidiol (CBD) on Seizure Frequency and Severity is Independent of Drug-Drug Interactions with other Anti-Epileptic Drugs (AEDs) (P4.271)
Objective: To determine if there is a difference in seizure frequency and severity between patients taking AEDs shown to interact… 
2009
2009
Stiripentol Changes Serum Concentration of Desmethylclobazam -Four Cases with CYP2C19 Polymorphism-
乳児重症ミオクロニーてんかんの治療薬であるスティリペントール（STP; 本邦未承認薬）はチトクロームP450（CYP）2C19の強力な阻害剤である。STP併用および非併用時におけるデスメチルクロバザム（DCLB）の血中濃度投与量比（LDR… 
1994
1994
Anticonvulsant activity of pyrrolo[1',2':1,2]imidazo[4,5-b]pyridines, pyrrolo[2',1':2,3]imidazo[4,5-c] pyridines and pyrrolo[2,1-f]purines in DBA/2 mice.
1993
1993
Molecular requirement for anticonvulsant activity in a series of thiazolo-1,4-benzodiazepine derivatives and comparison with classical benzodiazepines.
1993
1993
The Analysis of Clobazam and Its Metabolite Desmethylclobazam by High-Performance Liquid Chromatography
1992
1992
High-performance liquid chromatographic method for the determination of alprazolam in plasma using the column-switching technique.
1991
1991
The Analysis of Clobazam and Its Metabolite Desmethylclobazam by High‐Performance Liquid Chromatography
Summary The analysis of clobazam and its metabolite desmethylclobazam by high-performance liquid chromatography is described… 
1989
1989
HPLC method for simultaneous determination of clobazam and N-desmethylclobazam in human serum, rat serum and rat brain homogenates.
A method for simultaneous determination of clobazam (CBZ) and its active metabolite N-desmethylclobazam (DCBZ) in various… 
1988
1988
Tissue distribution of ethosuximide and clobazam in a seizure related fatality.
The case of a six-year-old male who died in a hospital while receiving several anticonvulsant drugs is described. Phenytoin… 
1980
1980
Electron-capture GLC determination of clobazam and desmethylclobazam in plasma.
Electron-capture GLC was utilized for simultaneous quantitation of clobazam, a 1,5-benzodiazepine derivative, and its active… 
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