Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

desmethylazelastine

Known as: 4-(4-chlorobenzyl)-2-(perhydroazepinyl-(4))-1(2H)-phthala zinone 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
A selective and sensitive high performance liquid chromatography-tandem mass spectrometric method was developed for the analysis… Expand
  • figure 1
  • table 1
  • table 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
It is generally known that the substrates and/or inhibitors of cytochrome P450 (CYP) 3A4 and P-glycoprotein (P-gp) overlap with… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Azelastine, an antiallergy and antiasthmatic drug, has been reported to be mainly N-demethylated to desmethylazelastine in humans… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1999
1999
Azelastine, an antiallergy and antiasthmatic drug, has been reported to be metabolized mainly to desmethylazelastine and 6… Expand
  • figure 1
  • figure 2
  • table 1
Is this relevant?
1999
1999
Azelastine hydrochloride [4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4yl )-1-(2 H)-phthalazinone… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
1993
1993
Analytical methods have been developed for the simultaneous quantitation of azelastine (AZ) and desmethylazelastine (DAZ) in… Expand
Is this relevant?
1993
1993
The correlation between the antiasthma activity of azelastine and the concentrations of azelastine and its major metabolite… Expand
Is this relevant?
1992
1992
Pharmacokinetics of azelastine (AZ) and its major active metabolite desmethylazelastine (DAZ) after iv or po administration of 1… Expand
Is this relevant?
1990
1990
We examined the effects of a new anti-asthmatic drug, azelastine, and its principal metabolite, desmethylazelastine, on the in… Expand
Is this relevant?
1987
1987
A manual-injection liquid chromatographic method using fluorescence detection permitted determination of a new antiasthmatic drug… Expand
Is this relevant?