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desacetylcephalothin

Known as: deacetylcephalothin 
National Institutes of Health

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2 relations

Broader (1)

Cephalothin
analogs & derivatives

Papers overview

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1987
1987
Inactivation of alanine racemase by beta-chloro-L-alanine released enzymatically from amino acid and peptide C10-esters of deacetylcephalothin.
The reactions of a set of amino acid and peptidyl C10-esters of deacetylcephalothin (1-5) have been examined with purified… 
1980
1980
A study of cephalothin and desacetylcephalothin in cerebrospinal fluid in therapy for experimental pneumococcal meningitis.
One explanation for the failure of cephalothin to cure patients with bacterial meningitis is that desacetylcephalothin, as in… 
1979
1979
Cephalothin kinetics: Before, during, and after cardiopulmonary bypass surgery
Cephalothin kinetics was studied in 5 patients the day before (PREOP), during (SURG), and the day after (POSTOP) cardiopulmonary… 
1979
1979
Pharmacokinetics of cephalothin: accumulation of its deacetylated metabolite in uremic patients.
The pharmacokinetics of cephalothin and its deacetyl metabolite were studied with use of a chemical assay involving high-pressure… 
1978
1978
Quantitation of Antibiotics by High-Pressure Liquid Chromatography: Cephalothin
A technique for quantitative determination of cephalothin and desacetylcephalothin in serum using a method based on high-pressure… 
1977
1977
Penetration of Cefamandole, Cephalothin, and Desacetylcephalothin into Fibrin Clots
The conversion of cephalothin into a less active metabolite (desacetylcephalothin) might influence its distribution in tissues… 
1977
1977
Metabolic disposition of cephalothin and deacetylcephalothin in children and adults: Comparison of high‐performance liquid chromatographic and microbial assay procedures
A highly specific method utilizing ion‐pair extraction and high‐pressure liquid chromatography has been developed for the… 
Highly Cited
1974
Highly Cited
1974
Analysis of cefoxitin, cephalothin and their deacylated metabolites in human urine by high-performance liquid chromatography.
1973
1973
Ion-pair extraction and high-speed liquid chromatography of cephalothin and deacetylcephalothin in human serum and urine.
Cephalothin and its major metabolite, deacetylcephalothin, have been analyzed in human serum and urine using high-speed ion… 
1970
1970
Paper chromatographic techniques for the determination of cephalothin and desacetylcephalothin in body fluids.
Paper chromatographic procedures may be used to detect cephalothin and its metabolite desacetylcephalothin in urine, plasma… 
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