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derrubone
National Institutes of Health
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1 relation
Broader (1)
Isoflavones
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Three isoflavones from Derris scandens (Roxb.) Benth and their cancer chemopreventive activity and in vitro antiproliferative effects.
C. Ito
,
T. Matsui
,
+4 authors
M. Itoigawa
Phytochemistry
2020
Corpus ID: 215818899
Three undescribed isoflavones, derriscandenon A, B, and C, together with seven known isoflavones were isolated and structurally…
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2015
2015
In-silico modeling studies of G-quadruplex with soy isoflavones having anticancerous activity
J. Tomar
Journal of Molecular Modeling
2015
Corpus ID: 25136094
Telomere forms t-loop and G-quadruplex as the protective structure and the formation of these structures hinder the telomerase…
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2014
2014
Identifying a C-terminal ATP binding sites-based novel Hsp90-Inhibitor in silico: a plausible therapeutic approach in Alzheimer's disease.
Shumaila Khalid
,
S. Paul
Medical hypotheses
2014
Corpus ID: 25839599
BACKGROUND Alzheimer's disease (AD) is a progressive brain disorder, which gradually and irreversibly destroys the intellectual…
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2014
2014
Identification and inhibition of C-terminal ATP-binding sites of Hsp90α through design of novel derrubone analogues as a plausible approach towards Alzheimer’s disease treatment
Shumaila Khalid
2014
Corpus ID: 56360758
The significant causative factors of Alzheimer's disease progression is the failure of the heat shock protein Hsp-90 to…
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2010
2010
The synthesis and evaluation of flavone and isoflavone chimeras of novobiocin and derrubone.
Jared R Mays
,
S. A. Hill
,
Justin T Moyers
,
B. Blagg
Bioorganic & medicinal chemistry
2010
Corpus ID: 21452697
The natural products novobiocin and derrubone have both demonstrated Hsp90 inhibition and structure-activity relationships have…
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2008
2008
Synthesis and evaluation of derrubone and select analogues.
Jedidiah M Hastings
,
M. Hadden
,
B. Blagg
The Journal of organic chemistry
2008
Corpus ID: 37506933
Recently, we reported that the natural product derrubone exhibits Hsp90 inhibitory activity. Due to its unique architectural…
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2007
2007
Derrubone, an inhibitor of the Hsp90 protein folding machinery.
M. Hadden
,
Lakshmi Galam
,
J. Gestwicki
,
R. Matts
,
B. Blagg
Journal of natural products
2007
Corpus ID: 28897080
High-throughput screening of a library of diverse molecules has identified derrubone ( 1), an isoflavone natural product from…
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