depyrimidination

The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2015
01219732015

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2009
2009
When DNA is damaged by ionizing radiation, the genes in a cell may acquire mutations or the cell could die. The smallest known… (More)
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2007
2007
The 3 million-base pair genome of Sulfolobus solfataricus likely undergoes depurination/depyrimidination frequently in vivo… (More)
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2003
2003
The primary purpose of this research is to examine the hypothesis that reactive oxygen species generated by estrogen quinonoids… (More)
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2001
2001
DNA damage induced by tetrachlorohydroquinone (Cl(4)HQ), the quinonoid metabolite of pentachlorophenol (PCP), was investigated in… (More)
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2000
2000
We investigated abasic site formation in calf thymus DNA after exposure to a model compound of lipid-derived peroxyl radical that… (More)
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1997
1997
The peroxy radical (ROO) is unique among reactive oxygen species implicated in the production of DNA damage in that it possesses… (More)
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1995
1995
The 2'-deoxy (2a) and 2'-ara-fluoro (3a) derivatives of zebularine [1-(beta-D-ribofuranosyl)-dihydropyrimidin-2-one, 1a] were… (More)
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1991
1991
MDBP, a mammalian sequence-specific DNA-binding protein, was found to recognize two sites in the major immediate-early (IE… (More)
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1986
1986
Treatment of intact lambda phage with the nonprotein chromophore of neocarzinostatin resulted in efficient phage inactivation and… (More)
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