Skip to search formSkip to main contentSkip to account menu

depyrimidination

The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase.
Human thymidine phosphorylase (hTP) is responsible for thymidine (dT) homeostasis, promotes angiogenesis, and is involved in… 
Highly Cited
2007
Highly Cited
2007
Mechanism of Abasic Lesion Bypass Catalyzed by a Y-family DNA Polymerase*
The 3 million-base pair genome of Sulfolobus solfataricus likely undergoes depurination/depyrimidination frequently in vivo… 
2000
2000
Formation of abasic sites in DNA by t-butyl peroxyl radicals: implication for potent genotoxicity of lipid peroxyl radicals.
1991
1991
Three MDBP sites in the immediate-early enhancer-promoter region of human cytomegalovirus.
1989
1989
An estradiol-dependent protein from chicken liver binds single-stranded DNA and RNA.
1986
1986
Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC.
Treatment of intact lambda phage with the nonprotein chromophore of neocarzinostatin resulted in efficient phage inactivation and… 
1982
1982
Mechanism of action of antitumor 3-(2-haloethyl) aryltriazenes on deoxyribonucleic acid.
1980
1980
Mechanism of benzo[a]pyrene diol epoxide induced deoxyribonucleic acid strand scission.
Approximately 1% of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BaP-diol epoxide… 
1975
1975
Endonuclease II of Escherichia coli: degradation of gammairradiated DNA.
Irradiation of DNA in a nitrogen atmosphere with 60Co gamma-radiation produces at least two types of damage. The first type leads… 
1974
1974
A comparative study of the relative ease of thermolytic depurination vs. depyrimidination in 2'-deoxynucleosides.
Following fusion, 2′-deoxynucleosides undergo thermolytic cleavage to produce furfuryl alcohol and water along with the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)