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deoxynucleoside kinase activity
Known as:
D. melanogaster deoxynucleoside kinase activity
, ms-dNK
, ATP:deoxynucleoside 5'-phosphotransferase activity
Â
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Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate. [EC:2.7.1.145]
National Institutes of Health
Topic mentions per year
Topic mentions per year
1976-2015
0
1
2
3
1976
2015
Papers overview
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2007
2007
Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs
Wolfgang Knecht
,
Elżbieta Rozpędowska
,
+7 authors
Jan Piskur
Gene Therapy
2007
Transduced deoxyribonucleoside kinases (dNK) can be used to kill recipient cells in combination with nucleoside prodrugs. The…Â
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2006
2006
New ultrasensitive 32P-postlabelling method for the analysis of 3,N4-etheno-2'-deoxycytidine in human urine.
X. Sun
,
A. Karlsson
,
Helmut Bartsch
,
Jayaprakash K. Nair
Biomarkers : biochemical indicators of exposure…
2006
Etheno-DNA adducts are generated from exogenous carcinogens such as vinyl chloride and urethane and also from endogenous lipid…Â
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2003
2003
Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional…
Jan Balzarini
,
Ana-Isabel Hernández
,
+4 authors
MarÃa-Jesús Pérez-Pérez
Molecular pharmacology
2003
5'-O-Trityl derivatives of thymidine (dThd), (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU), and their acyclic analogs 1-[(Z)-4…Â
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2002
2002
Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation.
Wolfgang Knecht
,
Gitte Ebert Petersen
,
Birgitte Munch-Petersen
,
Jure Piškur
Journal of molecular biology
2002
In eukaryotic cells deoxyribonucleoside kinases belonging to three phylogenetic sub-families have been found: (i) thymidine…Â
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2001
2001
Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea.
X. Zheng
,
M. Johansson
,
A. Karlsson
Molecular pharmacology
2001
The multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster (Dm-dNK) can be expressed in human cells with retained…Â
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2001
2001
Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol.
X. Zheng
,
M. Johansson
,
A. Karlsson
Biochemical and biophysical research…
2001
We have recently shown that the overexpression of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (Dm-dNK) in…Â
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2000
2000
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
X. Zheng
,
M. Johansson
,
A. Karlsson
The Journal of biological chemistry
2000
Nucleoside kinases from several species are investigated as "suicide genes" for treatment of malignant tumors by combined gene…Â
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2000
2000
Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants.
Birgitte Munch-Petersen
,
Wolfgang Knecht
,
Christof Lenz
,
Leif Søndergaard
,
Jan Piskur
The Journal of biological chemistry
2000
The occurrence of a deoxyribonucleoside kinase in Drosophila melanogaster (Dm-dNK) with remarkably broad substrate specificity…Â
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2000
2000
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.
Wolfgang Knecht
,
Birgitte Munch-Petersen
,
Jan Piskur
Journal of molecular biology
2000
In contrast to all known deoxyribonucleoside kinases, a single highly efficient deoxyribonucleoside kinase from Drosophila…Â
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1985
1985
Epstein-Barr virus induces a unique pyrimidine deoxynucleoside kinase activity in superinfected and virus-producer B cell lines.
Thomas E. Stinchcombe
,
Wendy Clough
Biochemistry
1985
Epstein-Barr (EB) virus induces a new pyrimidine deoxynucleoside kinase [thymidine kinase (dTk)] activity in Raji B lymphocyte…Â
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