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deoxyhypusine monooxygenase activity

Known as: DOHH activity, deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating), deoxyhypusine hydroxylase activity 
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O… Expand
National Institutes of Health

Papers overview

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2016
2016
Replication of the human immunodeficiency virus type 1 (HIV-1) is dependent on eIF5A hypusination. Hypusine is formed post… Expand
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2011
2011
The eukaryotic translation initiation factor 5A (eIF5A) is the only cellular protein that contains an unusual amino acid… Expand
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2007
2007
Deoxyhypusine hydroxylase is the second of the two enzymes that catalyzes the maturation of eukaryotic initiation factor 5A… Expand
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1989
1989
The inhibition of deoxyhypusine hydroxylase was studied in vitro. Of the polyamines tested, spermine and its homologue thermine… Expand
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1986
1986
Two procedures for rapid assay of deoxyhypusine hydroxylase activity are described. One of these assays measures changes in the… Expand
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