deoxyhypusine monooxygenase activity

Known as: DOHH activity, deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating), deoxyhypusine hydroxylase activity

Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O…

National Institutes of Health

Papers overview

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2016

2016

Targeting deoxyhypusine hydroxylase activity impairs cap-independent translation initiation driven by the 5'untranslated region of the HIV-1, HTLV-1, and MMTV mRNAs.

C. J. Cáceres, J. Angulo, Nataly Contreras, K. Pino, J. Vera-Otarola, M. López-Lastra
Antiviral research
2016
Corpus ID: 20886002

2011

2011

Assay of deoxyhypusine hydroxylase activity.

J. H. Park, E. Wolff, M. Park
Methods in molecular biology
2011
Corpus ID: 25411063

The eukaryotic translation initiation factor 5A (eIF5A) is the only cellular protein that contains an unusual amino acid…

2007

2007

Molecular cloning and functional expression of bovine deoxyhypusine hydroxylase cDNA and homologs.

Jenq-Kuen Huang, Yalu Cui, Chieh-Hua Chen, Denae J Clampitt, Chi‐Tsai Lin, L. Wen
Protein expression and purification
2007
Corpus ID: 20817850

1989

1989

Inhibition of deoxyhypusine hydroxylase by polyamines and by a deoxyhypusine peptide.

A. Abbruzzese, M. H. Park, S. Beninati, J. E. Folk
Biochimica et biophysica acta
1989
Corpus ID: 21191778

1986

1986

Indirect assays for deoxyhypusine hydroxylase using dual-label ratio changes and oxidative release of radioactivity.

A. Abbruzzese, M. H. Park, J. E. Folk
Analytical biochemistry
1986
Corpus ID: 26833273