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dense core granule maturation

Known as: dense core vesicle maturation 
Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense… Expand
National Institutes of Health

Papers overview

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2017
2017
GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans
Apoptotic cells generated by programmed cell death are engulfed by phagocytes and enclosed within plasma membrane–derived… Expand
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2016
2016
Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila
Unbiased genetic approaches have a unique ability to identify novel genes associated with specific biological pathways. Thanks to… Expand
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2015
2015
Pharyngeal pumping inhibition and avoidance by acute exposure to high CO2 levels are both regulated by the BAG neurons via different molecular pathways.
Carbon dioxide (CO2) is a key molecule in many biological processes. Studies in humans, mice, D. melanogaster, C. elegans… Expand
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2012
2012
TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans
Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a… Expand
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Highly Cited
2009
Highly Cited
2009
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans
Small guanosine triphosphatases of the Rab family regulate intracellular vesicular trafficking. Rab2 is highly expressed in the… Expand
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Highly Cited
2009
Highly Cited
2009
Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2
Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic… Expand
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