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delta-12 fatty acid desaturase

Known as: oleic acid delta(12)-desaturase, FAD2 fatty acid desaturase, oleate n-6 desaturase 
National Institutes of Health

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Fatty Acid Desaturases

Papers overview

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2011
2011
Elevated Delta-6 desaturase (FADS2) gene expression in the prefrontal cortex of patients with bipolar disorder.
2006
2006
Functional characterization of Δ9 and ω9 desaturase genes in Mortierella alpina 1S-4 and its derivative mutants
Cloning and characterization of the Δ9 desaturase (Δ9I) gene of a fungus, Mortierella alpina 1S-4, was previously reported. In… 
2004
2004
A novel carotenoid biosynthesis gene coding for ζ-carotene desaturase: functional expression, sequence and phylogenetic origin
A DNA fragment which has been isolated previously from an Anabaena DNA expression library was subcloned. The corresponding… 
2003
2003
15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma.
The peroxisome proliferator-activated receptor-gamma (PPARgamma) high-affinity ligand, 15-deoxy-Delta-12,14-PGJ(2) (15d-PGJ(2… 
Highly Cited
2001
Highly Cited
2001
A vertebrate fatty acid desaturase with Delta 5 and Delta 6 activities.
Delta5 and Delta6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty… 
2001
2001
Activity of human Delta5 and Delta6 desaturases on multiple n-3 and n-6 polyunsaturated fatty acids.
Yeast co-expressing human elongase and desaturase genes were used to investigate whether the same desaturase gene encodes an… 
2001
2001
Consequences of omega -6-oleate desaturase deficiency on lipid dynamics and functional properties of mitochondrial membranes of Arabidopsis thaliana.
We probed the role of the polyunsaturated fatty acids on the dynamic and functional properties of mitochondrial membranes using… 
2000
2000
A second functional delta5 fatty acid desaturase in the cellular slime mould Dictyostelium discoideum.
A cDNA with homology to fatty acid desaturases was selected by searching the cDNA data bank of Dictyostelium discoideum (http… 
Highly Cited
1994
Highly Cited
1994
Cloning of a Higher-Plant Plastid [omega]-6 Fatty Acid Desaturase cDNA and Its Expression in a Cyanobacterium
Oligomers based on amino acids conserved between known plant [omega]-3 and cyanobacterium [omega]-6 fatty acid desaturases were… 
1989
1989
Effects of dietary fish oil on human mammary carcinoma and on lipid-metabolizing enzymes
The growth rate of a human mammary carcinoma, MX-1, was significantly reduced in athymic “nude” mice fed fish oil. Tumors from… 
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