deficiency of triacylglycerol lipase

Known as: lipase deficiency 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia
Hypertriglyceridemia is a hallmark of many disorders, including metabolic syndrome, diabetes, atherosclerosis and obesity. A well… (More)
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Highly Cited
2002
Highly Cited
2002
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis.
Hormone-sensitive lipase (HSL) is expressed predominantly in white and brown adipose tissue where it is believed to play a… (More)
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Highly Cited
2002
Highly Cited
2002
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle.
Hormone-sensitive lipase (HSL) is believed to play an important role in the mobilization of fatty acids from triglycerides (TG… (More)
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2002
2002
Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation.
Hormone-sensitive lipase (HSL, E.C.3.1.1.3, gene designation Lipe) is reportedly the major cholesteryl esterase of adrenal cortex… (More)
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Highly Cited
2001
Highly Cited
2001
The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice.
OBJECTIVE To directly ascertain the physiological roles in adipocytes of hormone-sensitive lipase (HSL; E.C. 3.1.1.3), a… (More)
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Highly Cited
1996
Highly Cited
1996
Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice.
We previously showed that human apoC-III expression in transgenic mice causes hypertriglyceridemia due to the accumulation of… (More)
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1990
1990
Structure and polymorphic map of human lipoprotein lipase gene.
Lipoprotein lipase (LPL) catalyzes the key step for the removal of triacylglycerol-rich lipoproteins from the circulation. In… (More)
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1989
1989
Lipoprotein abnormalities associated with lipopolysaccharide-induced lecithin: cholesterol acyltransferase and lipase deficiency.
Density gradient ultracentrifugation was used to isolate and characterize the plasma lipoproteins from African green monkeys… (More)
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1984
1984
Effect of intrajejunal acidity on aqueous phase bile acid and lipid concentrations in pancreatic steatorrhoea due to cystic fibrosis.
We have investigated whether jejunal hyperacidity leads to bile acid precipitation and thus limits lipid solubilisation in… (More)
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1983
1983
Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse.
Two triglyceride lipases, lipoprotein lipase and hepatic triglyceride lipase, participate in the metabolism of plasma… (More)
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