deficiency of triacylglycerol lipase

Hypertriglyceridemia is a hallmark of many disorders, including metabolic syndrome, diabetes, atherosclerosis and obesity. A well… Expand

Hormone-sensitive lipase (HSL) is expressed predominantly in white and brown adipose tissue where it is believed to play a… Expand

Hormone-sensitive lipase (HSL) is believed to play an important role in the mobilization of fatty acids from triglycerides (TG… Expand

OBJECTIVE To directly ascertain the physiological roles in adipocytes of hormone-sensitive lipase (HSL; E.C. 3.1.1.3), a… Expand

The mutations cld (combined lipase deficiency) and lec23 disrupt in a similar manner the expression of lipoprotein lipase (LPL… Expand

We previously showed that human apoC-III expression in transgenic mice causes hypertriglyceridemia due to the accumulation of… Expand

Naturally occurring mutations in the mouse provide a unique resource for identifying genes and characterizing proteins involved… Expand

Lipoprotein lipase (LPL) catalyzes the key step for the removal of triacylglycerol-rich lipoproteins from the circulation. In… Expand

Density gradient ultracentrifugation was used to isolate and characterize the plasma lipoproteins from African green monkeys… Expand

We have investigated whether jejunal hyperacidity leads to bile acid precipitation and thus limits lipid solubilisation in… Expand