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deacylcortivazol

Known as: 11 beta,17,21-trihydroxy-6,16 alpha-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno(3,2-c)pyrazol-20-one, bimedrazole 
National Institutes of Health

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Broader (1)

Pregnatrienes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors.
We previously reported that several point mutations in the ligand binding domain (LBD) of glucocorticoid receptors (GRs… 
2005
2005
LEM 1 , an ATP-binding-cassette transporter , selectively modulates the biological potency of steroid hormones ( glucocorticoid receptor / yeast / PDR 5 / STSI )
The rat glucocorticoid receptor confers hormone-dependent transcriptional enhancement when expressed in yeast, thereby enabling… 
1999
1999
Functional analysis of R651 mutations in the putative helix 6 of rat glucocorticoid receptors
1993
1993
Binding of RU486 and deacylcortivazol to the glucocorticoid receptor is insensitive to sulfhydryl-modifying agents
1993
1993
Computer stimulation of interaction of deacylcortivazol with d(TGTTCT)2.
We have obtained models for the interaction of deacylcortivazol (DAC) with the hexanucleotide duplex d(TGTTCT)2 (DNA) by computer… 
1988
1988
Description and analysis of differential sensitivity to glucocorticoids in Fao cells.
1984
1984
Glucocorticoid versus antiglucocorticoid activity: can a single functional group modification of glucocorticoid steroids always convey antiglucocorticoid activity?
Single functional group modifications of glucocorticoid steroids have been performed in an effort to obtain antiglucocorticoids… 
1982
1982
Non-glucocorticoid receptor-mediated effects of the potent glucocorticoid deacylcortivazol.
Deacylcortivazol (DAC), a potent glucocorticoid, contains a phenyl-pyrazole moiety fused to the 2--3 position of the traditional… 
1981
1981
Deacylcortivazol, a potent glucocorticoid with unusual structure and unusual anti-leukemic cell activity.
The currently accepted dogma of steroid action states that the structure required for potent glucocorticoid action must at least… 
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