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- Publications
- Influence
Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies
- D. Tasdemir, M. Kaiser, +4 authors P. Rueedi
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 April 2006
ABSTRACT Trypanosomiasis and leishmaniasis are important parasitic diseases affecting millions of people in Africa, Asia, and South America. In a previous study, we identified several flavonoid… Expand
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.
- T. Schmidt, Muharrem Ak, U. Mrowietz
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 2007
Dimethyl fumarate (DMF) is used successfully to treat psoriasis. In spite of its proven clinical efficacy, the mode of metabolism and the pharmacodynamics of DMF are still not completely understood.… Expand
Characterization of rubber particles and rubber chain elongation in Taraxacum koksaghyz
- T. Schmidt, M. Lenders, +7 authors C. S. Gronover
- Chemistry, Medicine
- BMC Biochemistry
- 19 February 2010
BackgroundNatural rubber is a biopolymer with exceptional qualities that cannot be completely replaced using synthetic alternatives. Although several key enzymes in the rubber biosynthetic pathway… Expand
Pinoresinol-lariciresinol reductases with different stereospecificity from Linum album and Linum usitatissimum.
- Cosima B I von Heimendahl, K. Schaefer, P. Eklund, R. Sjöholm, T. Schmidt, E. Fuss
- Biology, Medicine
- Phytochemistry
- 1 June 2005
Recently it was found that cell cultures and plants of Linum species contain lignans of various chemical structures. The stereochemistry of these compounds differ among species. Cell cultures of L.… Expand
Biogas Production from Sugarcane Waste: Assessment on Kinetic Challenges for Process Designing
- L. Janke, A. Leite, +4 authors W. Stinner
- Environmental Science, Medicine
- International journal of molecular sciences
- 31 August 2015
Biogas production from sugarcane waste has large potential for energy generation, however, to enable the optimization of the anaerobic digestion (AD) process each substrate characteristic should be… Expand
The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II.
- T. Schmidt, S. A. Khalid, +19 authors A. G. Tempone
- Medicine
- Current medicinal chemistry
- 2012
Infections with protozoan parasites are a major cause of disease and mortality in many tropical countries of the world. Diseases caused by species of the genera Trypanosoma (Human African… Expand
Structure-Activity Relationships of Sesquiterpene Lactones
- T. Schmidt
- Biology
- 2006
ABSTRACT: Sesquiterpene lactones (STLs) are one of the largest biogenetically homogenous groups of natural products known. Currently, the Dictionary of Natural Products holds a total of over 11000… Expand
Pharmacological properties of the extract and some isolated compounds of Clausena lansium stem bark: anti-trichomonal, antidiabetic, anti-inflammatory, hepatoprotective and antioxidant effects.
- A. C. Adebajo, E. O. Iwalewa, +8 authors E. Verspohl
- Biology, Medicine
- Journal of ethnopharmacology
- 25 February 2009
ETHNOPHARMACOLOGICAL RELEVANCE
Clausena lansium (Fool's Curry Leaf) is used for various ethnomedical conditions in some countries, including bronchitis, malaria, viral hepatitis, acute and chronic… Expand
The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L.
- A. Nour, S. A. Khalid, M. Kaiser, R. Brun, W. E. Abdalla, T. Schmidt
- Biology, Medicine
- Journal of ethnopharmacology
- 4 May 2010
AIM OF THE STUDY
The dichloromethane extract prepared from aerial parts of Ageratum conyzoides L. (Asteraceae), a plant commonly used in folk medicine for a number of illnesses including sleeping… Expand
3-O-Galloylated Procyanidins from Rumex acetosa L. Inhibit the Attachment of Influenza A Virus
- A. Derksen, Andreas Hensel, +5 authors J. Kühn
- Biology, Medicine
- PloS one
- 10 October 2014
Infections by influenza A viruses (IAV) are a major health burden to mankind. The current antiviral arsenal against IAV is limited and novel drugs are urgently required. Medicinal plants are known as… Expand