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darexaban glucuronide

 
National Institutes of Health

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2014
2014
We investigated the effects of ketoconazole on the pharmacokinetics (PK) of the direct clotting factor Xa inhibitor darexaban… Expand
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2013
2013
1. The absorption, metabolism and excretion of darexaban (YM150), a novel oral direct factor Xa inhibitor, were investigated… Expand
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2013
2013
AIMS We investigated the effects of rifampicin on the pharmacokinetics (PK) of the direct clotting factor Xa inhibitor darexaban… Expand
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2013
2013
The oral direct factor Xa inhibitor darexaban administered intraduodenally prevented venous thrombus formation in both rats and… Expand
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2013
2013
Here, we investigated the anticoagulant effects of darexaban in mice and human plasma in vitro, effects of darexaban in… Expand
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2013
2013
BACKGROUND Darexaban (YM150) is a potent direct factor Xa (FXa) inhibitor developed for the prophylaxis of venous and arterial… Expand
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2013
2013
BACKGROUND Darexaban is a potent direct factor Xa (FXa) inhibitor developed for prophylaxis of venous and arterial thromboembolic… Expand
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2012
2012
Darexaban maleate is a novel oral direct factor Xa inhibitor. Darexaban glucuronide (YM-222714) was the major component in plasma… Expand
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2012
2012
Most synthetic factor Xa (FXa) and thrombin inhibitors examined in pharmacokinetic studies and phase II/III clinical trials have… Expand
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2011
2011
Darexaban (YM150) is an oral factor Xa inhibitor developed for the prophylaxis of venous and arterial thromboembolic disease… Expand
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