darexaban glucuronide
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
We investigated the effects of ketoconazole on the pharmacokinetics (PK) of the direct clotting factor Xa inhibitor darexaban…
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT
1. The absorption, metabolism and excretion of darexaban (YM150), a novel oral direct factor Xa inhibitor, were investigated…
Background. Darexaban (YM150) is a potent direct factor Xa (FXa) inhibitor developed for the prophylaxis of venous and arterial…
The clinical pharmacokinetics, pharmacodynamics, safety and tolerability of darexaban after single and multiple once‐daily doses…
Darexaban maleate is a novel oral direct factor Xa inhibitor. Darexaban glucuronide (YM-222714) was the major component in plasma…