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dapivirine

Known as: 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino] benzonitrile, TMC120, TMC120-R147681 
A diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Dapivirine has activity against wild-type virus strains and strains harboring… 
National Institutes of Health

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Related topics

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Broader (1)

Pyrimidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Prep Adherence to Tenofovir-Based Therapeutics Seems Efficacious in Reducing HIV Infection Dissemination: A Comparative Evaluation on The Therapeutic Potency of Tenofovir-Based Prep & Dapivirine…
This dissertation is being archived for campus access to current students and staff only at the request of the author. 
2017
2017
The dapivirine ring design guide: Human-centered design research to increase uptake and use.
The U.S. Agency for International Developments (USAIDs) Center for Accelerating Innovation and Impact (CII) and Office of HIV… 
2017
2017
More Recent PrEP Studies : Real-World Effects
  • 2017
  • Corpus ID: 42597394
Preexposure prophylaxis (PrEP) is an integral part of HIV prevention.1,2 In numerous clinical trials of biomedical antiretroviral… 
2017
2017
OPTIONS Consortium: Optimizing Prevention Technology Introduction On Schedule Speak my language! Using digital media to reach and engage adolescents on oral PrEP
2016
2016
Dapivirine Vaginal Ring Showed Modest Efficacy at Preventing HIV Infection in African Women
Preexposure prophylaxis with antiretroviral therapy can lower risk for HIV acquisition, but the efficacy of this approach depends… 
2008
2008
Pharmacokinetic assessment of an anti-HIV dapivirine vaginal microbicide gel (Gel-002).
2007
2007
ONIOM DFT/PM3 calculations on the interaction between dapivirine and HIV-1 reverse transcriptase, a theoretical study.
Theoretical investigations of the interaction between dapivirine and the HIV-1 RT binding site have been performed by the ONIOM2… 
2007
2007
Sustained delivery of microbicide dapivirine using intra-vaginal rings: an independent clinical assessment of safety and drug delivery in women.
2006
2006
In Vitro Release of the Microbicidal Compound TMC120 from a Silicone Intravaginal Ring System
2006
2006
In Vitro Release of the Microbicidal Compound TMC120 from a Silicone Intravaginal Ring System