dabigatran

Known as: Dabigatran [Chemical/Ingredient], N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine 
A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Specific reversal agents for non-vitamin K antagonist oral anticoagulants are lacking. Idarucizumab, an antibody… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND The comparative safety of dabigatran versus warfarin for treatment of nonvalvular atrial fibrillation in general… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Dabigatran and warfarin have been compared for the treatment of acute venous thromboembolism (VTE) in a previous trial… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Dabigatran 150 and 110 mg twice a day and warfarin are effective for stroke prevention in atrial fibrillation. The… (More)
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Highly Cited
2010
Highly Cited
2010
Highly Cited
2010
BACKGROUND The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial compared dabigatran 110 mg BID (D110) and… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Recent studies have investigated alternatives to warfarin for stroke prophylaxis in patients with atrial fibrillation… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The direct oral thrombin inhibitor dabigatran has a predictable anticoagulant effect and may be an alternative therapy… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases the risk of hemorrhage and is… (More)
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Highly Cited
2009
Highly Cited
2009
 
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