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dabigatran etexilate mesylate
Known as:
Beta-alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester, methanesulfonate
, Etexilate Mesylate, Dabigatran
, Mesylate, Dabigatran Etexilate
An orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct thrombin inhibitor with anticoagulant…
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National Institutes of Health
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Related topics
Related topics
5 relations
Narrower (1)
Pradaxa
Thrombomodulin Alfa
dabigatran etexilate 150 MG Oral Capsule [Pradaxa]
Broader (2)
dabigatran
dabigatran etexilate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects
P. Hsyu
,
Daniela Soriano Pignataro
,
K. Matschke
European Journal of Clinical Pharmacology
2016
Corpus ID: 7436438
PurposeBosutinib, a dual Src and Abl tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia, demonstrated…
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2016
2016
Appropriate Apixaban Dosing: Prescribers Take Note.
J. Weitz
,
J. Eikelboom
JAMA cardiology
2016
Corpus ID: 205105289
Appropriate Apixaban Dosing: Prescribers Take Note Jeffrey Weitz;John Eikelboom; JAMA Cardiology
Highly Cited
2015
Highly Cited
2015
Risk of bleeding with dabigatran in atrial fibrillation.
Inmaculada Hernandez
,
S. Baik
,
A. Piñera
,
Yuting Zhang
JAMA internal medicine
2015
Corpus ID: 23049515
IMPORTANCE It remains unclear whether dabigatran etexilate mesylate is associated with higher risk of bleeding than warfarin…
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2015
2015
Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis
Eric T. Alexander
,
Allyson R. Minton
,
Candace S. Hayes
,
A. Goss
,
J. van Ryn
,
S. Gilmour
Cancer biology & therapy
2015
Corpus ID: 205878484
Cancer is often associated with an increased risk of thrombotic events which are exacerbated by treatment with chemotherapeutics…
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2014
2014
Transfer of Dabigatran and Dabigatran Etexilate Mesylate Across the Dually Perfused Human Placenta
P. Bapat
,
R. Kedar
,
+4 authors
G. Koren
Obstetrics and gynecology
2014
Corpus ID: 11412627
OBJECTIVE: To assess the transplacental pharmacokinetics at term of the oral thrombin inhibitor, dabigatran, and its prodrug…
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Highly Cited
2014
Highly Cited
2014
Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
O. Grottke
,
J. van Ryn
,
H. Spronk
,
R. Rossaint
Critical Care
2014
Corpus ID: 18518847
IntroductionNew oral anticoagulants are effective alternatives to warfarin. However, no specific reversal agents are available…
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2014
2014
Validated stability-indicating high performance liquid chromatographic assay method for the determination of Dabigatran Etexilate Mesylate.
P. Shelke
2014
Corpus ID: 28934029
Dabigatran Etexilate Mesylate was subjected to different ICH recommended stress conditions. Degradation of drug occurs almost in…
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2013
2013
Something new under the sun? The Mediterranean diet and cardiovascular health.
S. Tracy
The New England journal of medicine
2013
Corpus ID: 34159054
The history of dietary guidelines for heart health — a project begun in the 1950s when the United States felt threatened by a…
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2013
2013
Usefulness of Dabigatran Etexilate as Periprocedural Anticoagulation Therapy for Atrial Fibrillation Ablation
H. Yamaji
,
T. Murakami
,
+6 authors
S. Kusachi
Clinical Drug Investigation
2013
Corpus ID: 10323862
BackgroundThe usefulness of dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF) has been…
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2012
2012
Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate…
Zhe-yi Hu
,
R. B. Parker
,
Vanessa L. Herring
,
S. Laizure
Analytical and Bioanalytical Chemistry
2012
Corpus ID: 20995403
AbstractDabigatran etexilate (DABE) is an oral prodrug that is rapidly converted by esterases to dabigatran (DAB), a direct…
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