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dabigatran etexilate mesylate

Known as: Beta-alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester, methanesulfonate, Etexilate Mesylate, Dabigatran, Mesylate, Dabigatran Etexilate 
An orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct thrombin inhibitor with anticoagulant… Expand
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

Pradaxa
Thrombomodulin Alfadabigatran etexilate 150 MG Oral Capsule [Pradaxa]

Broader (2)

dabigatrandabigatran etexilate

Papers overview

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2016
2016
Effect of bosutinib on the absorption of dabigatran etexilate mesylate, a P-glycoprotein substrate, in healthy subjects
PurposeBosutinib, a dual Src and Abl tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia, demonstrated… Expand
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Highly Cited
2015
Highly Cited
2015
Risk of bleeding with dabigatran in atrial fibrillation.
IMPORTANCE It remains unclear whether dabigatran etexilate mesylate is associated with higher risk of bleeding than warfarin… Expand
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2015
2015
Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis.
Cancer is often associated with an increased risk of thrombotic events which are exacerbated by treatment with chemotherapeutics… Expand
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2014
2014
Transfer of dabigatran and dabigatran etexilate mesylate across the dually perfused human placenta.
OBJECTIVE To assess the transplacental pharmacokinetics at term of the oral thrombin inhibitor, dabigatran, and its prodrug… Expand
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Highly Cited
2014
Highly Cited
2014
Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex-vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model
IntroductionNew oral anticoagulants are effective alternatives to warfarin. However, no specific reversal agents are available… Expand
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2014
2014
Method Validation for Stability Indicating Method of Related Substance in Active Pharmaceutical Ingredients Dabigatran Etexilate Mesylate by Reverse Phase Chromatography
To develop the stability indicating, highly accurate precise and linear method for related substance of the Dabigatran through… Expand
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2014
2014
Validated stability-indicating high performance liquid chromatographic assay method for the determination of Dabigatran Etexilate Mesylate.
Dabigatran Etexilate Mesylate was subjected to different ICH recommended stress conditions. Degradation of drug occurs almost in… Expand
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2013
2013
Usefulness of Dabigatran Etexilate as Periprocedural Anticoagulation Therapy for Atrial Fibrillation Ablation
BackgroundThe usefulness of dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF) has been… Expand
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2012
2012
GC Quantification of Residual hexylmethane sulfonate in Dabigatran etexilate mesylate
A simple and a quantitative Gas chromatography (GC) method with oncolumn injection technique have been developed for the… Expand
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2012
2012
Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate…
AbstractDabigatran etexilate (DABE) is an oral prodrug that is rapidly converted by esterases to dabigatran (DAB), a direct… Expand
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