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cytochrome P-450 CYP2D15 (dog)
Known as:
CYPIID15
, CYP2D15
, P450 DUT2
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Aryl Hydrocarbon Hydroxylases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
DUT2 - Gestion et management des organisations
fsimo
,
cgaid
2020
Corpus ID: 179342485
2016
2016
Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
Tania E Perez Jimenez
,
K. Mealey
,
T. Grubb
,
S. Greene
,
M. Court
Drug Metabolism and Disposition
2016
Corpus ID: 32876815
Tramadol is widely used to manage mild to moderately painful conditions in dogs. However, this use is controversial, since…
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Review
2011
Review
2011
Caracterização do gene cyp2d15 em canídeos domésticos e selvagens
Maria Constanza Rodriguez
2011
Corpus ID: 83106018
Cytochromes P450 (P450s) are a superfamily of hemoproteins consisting of approximately 500 members distributed among more than 70…
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2010
2010
Alternative to animal testing for new drugs: structural, functional and electrochemical studies of monkey CYP2C20 and dog CYP2D15
F. Rua
,
S. Sadeghi
,
G. D. Nardo
,
G. Gilardi
2010
Corpus ID: 90913128
Highly Cited
2003
Highly Cited
2003
Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450.
M. Shou
,
Ryan Norcross
,
+6 authors
T. Rushmore
Drug metabolism and disposition: the biological…
2003
Corpus ID: 43460383
Seven dog cytochromes p450 (p450s) were heterologously expressed in baculovirus-Sf21 insect cells. Of all enzymes examined…
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2003
2003
SUBSTRATE SPECIFICITY AND KINETIC PROPERTIES OF SEVEN HETEROLOGOUSLY EXPRESSED DOG CYTOCHROMES P 450
M. Shou
,
Ryan Norcross
,
+6 authors
T. Rushmore
2003
Corpus ID: 28040041
Seven dog cytochromes P450 (P450s) were heterologously expressed in baculovirus-Sf21 insect cells. Of all enzymes examined…
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Highly Cited
1999
Highly Cited
1999
Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib.
S. Paulson
,
L. Engel
,
+5 authors
G. Schoenhard
Drug metabolism and disposition: the biological…
1999
Corpus ID: 13162495
The pharmacokinetics of celecoxib, a cyclooxygenase-2 inhibitor, was characterized in beagle dogs. Celecoxib is extensively…
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Highly Cited
1998
Highly Cited
1998
Expression and characterization of canine cytochrome P450 2D15.
F. Roussel
,
D. B. Duignan
,
M. Lawton
,
R. Obach
,
C. Strick
,
D. Tweedie
Archives of biochemistry and biophysics
1998
Corpus ID: 26572275
CYP2D15 is the canine ortholog of human CYP2D6, the human CYP2D isoform involved in the metabolism of drugs such as…
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1998
1998
Regio- and stereoselectivity in propranolol metabolism by dog liver microsomes and the expressed dog CYP2D15.
T. Tasaki
,
H. Iwata
,
A. Kazusaka
,
S. Fujita
Journal of biochemistry
1998
Corpus ID: 23220720
We have studied the regio- and stereoselectivity of ring-hydroxylation and N-desisopropylation of S(-)- and R(+)-propranolol…
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1998
1998
Expression and characterization of dog CYP2D15 using baculovirus expression system.
T. Tasaki
,
A. Nakamura
,
+7 authors
S. Fujita
Journal of biochemistry
1998
Corpus ID: 45106932
Dog CYP2D15 was expressed in Sf9 cells with a recombinant baculovirus. Infection of Sf9 insect cells with a recombinant dog…
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