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cytochrome P-450 CYP2D15 (dog)

Known as: CYPIID15, CYP2D15, P450 DUT2 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
012319982016

Related topics

Related topics

1 relation

Broader (1)

Aryl Hydrocarbon Hydroxylases

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
cytochrome P-450 CYP2D15 (dog)
Aryl Hydrocarbon Hydroxylases

Papers overview

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2016
2016
Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: Species comparison and identification of responsible canine cytochrome P-450s (CYPs).
Tramadol is widely used to manage mild to moderately painful conditions in dogs. However, this use is controversial since… (More)
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2012
2012
Expression profiles of metabolic enzymes and drug transporters in the liver and along the intestine of beagle dogs.
Beagle dogs are widely used in preclinical pharmacokinetic, safety, and formulation studies. However, little is known about… (More)
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2003
2003
Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450.
Seven dog cytochromes p450 (p450s) were heterologously expressed in baculovirus-Sf21 insect cells. Of all enzymes examined… (More)
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1999
1999
Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib.
The pharmacokinetics of celecoxib, a cyclooxygenase-2 inhibitor, was characterized in beagle dogs. Celecoxib is extensively… (More)
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1998
1998
Expression and characterization of canine cytochrome P450 2D15.
CYP2D15 is the canine ortholog of human CYP2D6, the human CYP2D isoform involved in the metabolism of drugs such as… (More)
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1998
1998
Regio- and stereoselectivity in propranolol metabolism by dog liver microsomes and the expressed dog CYP2D15.
We have studied the regio- and stereoselectivity of ring-hydroxylation and N-desisopropylation of S(-)- and R(+)-propranolol… (More)
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1998
1998
Expression and characterization of dog CYP2D15 using baculovirus expression system.
Dog CYP2D15 was expressed in Sf9 cells with a recombinant baculovirus. Infection of Sf9 insect cells with a recombinant dog… (More)
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