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cytochrome P-450 CYP2D15 (dog)

Known as: CYPIID15, CYP2D15, P450 DUT2 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Aryl Hydrocarbon Hydroxylases

Papers overview

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2020
2020
DUT2 - Gestion comptable et financière
2020
2020
DUT2 - Gestion et management des organisations
2016
2016
Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
Tramadol is widely used to manage mild to moderately painful conditions in dogs. However, this use is controversial, since… Expand
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2010
2010
Alternative to animal testing for new drugs: structural, functional and electrochemical studies of monkey CYP2C20 and dog CYP2D15
Highly Cited
2003
Highly Cited
2003
Substrate specificity and kinetic properties of seven heterologously expressed dog cytochromes p450.
Seven dog cytochromes p450 (p450s) were heterologously expressed in baculovirus-Sf21 insect cells. Of all enzymes examined… Expand
2003
2003
SUBSTRATE SPECIFICITY AND KINETIC PROPERTIES OF SEVEN HETEROLOGOUSLY EXPRESSED DOG CYTOCHROMES P 450
Seven dog cytochromes P450 (P450s) were heterologously expressed in baculovirus-Sf21 insect cells. Of all enzymes examined… Expand
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Highly Cited
1999
Highly Cited
1999
Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib.
The pharmacokinetics of celecoxib, a cyclooxygenase-2 inhibitor, was characterized in beagle dogs. Celecoxib is extensively… Expand
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Highly Cited
1998
Highly Cited
1998
Expression and characterization of canine cytochrome P450 2D15.
CYP2D15 is the canine ortholog of human CYP2D6, the human CYP2D isoform involved in the metabolism of drugs such as… Expand
1998
1998
Regio- and stereoselectivity in propranolol metabolism by dog liver microsomes and the expressed dog CYP2D15.
We have studied the regio- and stereoselectivity of ring-hydroxylation and N-desisopropylation of S(-)- and R(+)-propranolol… Expand
1998
1998
Expression and characterization of dog CYP2D15 using baculovirus expression system.
Dog CYP2D15 was expressed in Sf9 cells with a recombinant baculovirus. Infection of Sf9 insect cells with a recombinant dog… Expand
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