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cytochrome P-450 CYP121
Known as:
CYP121
, CYP450 MT2
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Cytochrome P450
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis.
H. Davis
,
Madeline E. Kavanagh
,
Tudor Balan
,
C. Abell
,
A. Coyne
Bioorganic & Medicinal Chemistry Letters
2016
Corpus ID: 206269709
2016
2016
Determination of Bucky ball pathway and binding domains via its protein interactors
J. Lewis
,
Prajwal N. Deshikar
,
Fnu Nagajyothi
,
H. Tanowitz
2016
Corpus ID: 22210763
Mycobacteriophages have played a central role in the study of tuberculosis by allowing for the genetic manipulation of…
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2015
2015
Fragment-based drug discovery of potent and selective CYP121 inhibitors for tuberculosis
Madeline E. Kavanagh
2015
Corpus ID: 89785651
Highly Cited
2007
Highly Cited
2007
Rapid P450 Heme Iron Reduction by Laser Photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1
A. J. Dunford
,
K. J. McLean
,
+4 authors
A. Munro
Journal of Biological Chemistry
2007
Corpus ID: 13732136
We demonstrate that photoexcitation of NAD(P)H reduces heme iron of Mycobacterium tuberculosis P450s CYP121 and CYP51B1 on the…
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Review
2006
Review
2006
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.
K. J. McLean
,
A. J. Dunford
,
+7 authors
A. Munro
Biochemical Society Transactions
2006
Corpus ID: 24061840
An extraordinary array of P450 (cytochrome P450) enzymes are encoded on the genome of the human pathogen Mycobacterium…
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2003
2003
Cytochromes P 450 : novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis
A. Munro
,
K. J. McLean
,
+8 authors
D. Leys
2003
Corpus ID: 11234059
Novel drug strategies are desperately needed to combat the global threat posed by multidrug-resistant strains of Mycobacterium…
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