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cystatin E protein

Known as: Cystatin E, Cystatin-6, CST6 Cystatin 
A cystatin subtype that has a diverse tissue distribution, target specificity, and functions as an endogenous inhibitor of lysosomal cysteine… Expand
National Institutes of Health

Papers overview

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2018
2018
Protein activity is often regulated by altering the oligomerization state. One mechanism of multimerization involves domain… Expand
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2017
2017
The ratio between proteases and their inhibitors is unbalanced in cancer. The cysteine protease inhibitor cystatin C is… Expand
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2017
2017
The asparaginyl endopeptidase legumain and its inhibitor cystatin E/M are endogenously glycosylated. However, little is known… Expand
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2016
2016
ABSTRACT We and others have shown that the cystatin E/M gene is inactivated in primary human tumors, pointing to its role as a… Expand
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2014
2014
TBX2 is an oncogenic transcription factor known to drive breast cancer proliferation. We have identified the cysteine protease… Expand
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2012
2012
Legumain, an asparaginyl endopeptidase, is up-regulated in tumour and tumour-associated cells, and is linked to the processing of… Expand
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Highly Cited
2009
Highly Cited
2009
BackgroundHigh activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and… Expand
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Highly Cited
2008
Highly Cited
2008
DNA hypermethylation-mediated gene silencing is a frequent and early contributor to aberrant cell growth and invasion in cancer… Expand
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2008
2008
We have previously localized a cervical cancer tumor suppressor gene to a 300 kb interval of 11q13. Analysis of candidate genes… Expand
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Highly Cited
1997
Highly Cited
1997
A novel human cystatin gene was identified in a differential display comparison aimed at the isolation of transcriptionally… Expand
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