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CST6 gene

Known as: CYSTATIN 6, CYSTATIN M, CST6 
This gene plays a role in the regulation of protein degradation.
National Institutes of Health

Related topics

Related topics

5 relations
Breast CarcinomaCST6 protein, humanProtein Degradation InhibitionRegulation of Proteolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The association of protein expression of CST6 with osteoporosis and establishment of prediction model of bone metastasis in breast cancer
Highly Cited
2015
Highly Cited
2015
Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients
Gene-specific methylation alterations in breast cancer have been suggested to occur early in tumorigenesis and have the potential… 
2014
2014
Abstract 4813: DNA methylation of tumor suppressor and metastasis suppressor genes in primary tumors, circulating tumor cells and cell free DNA in the same breast cancer patients
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Introduction: Blood based specimens such as Circulating… 
2013
2013
Analysis of legumain and cystatin 6 expression at the maternal–fetal interface in pigs
Cathepsins (CTSs), a family of lysosomal cysteine proteases, and their inhibitors, cystatins (CSTs), play a critical role in… 
2013
2013
Supplementary Figure and Table Legends
Supplementary Figure 1. A comparison of promoter methylation status, as determined by bisulphite sequencing and MSP, and… 
Review
2013
Review
2013
Significance of suppressor gene CST6 and its abnormal methylation in cancer
CST6 or cystatin E/M is first identified in breast cancer cells,which is a novel tumor suppressor gene inhibiting the function of… 
Review
2011
Review
2011
CST6 (cystatin E/M)
Review on CST6 (cystatin E/M), with data on DNA, on the protein encoded, and where the gene is implicated. 
2009
2009
Frequent Loss of Cystatin E/M Expression Implicated in the Progression of Prostate Cancer
Cystatin E/M (CST6) is a natural inhibitor of lysosomal cysteine proteases. Recent studies have shown that experimental… 
2008
2008
Prognostic significance of RASSF1A, CST6 and KLK10 methylation status in early breast cancer.
2627 Introduction . Epigenetic silencing of tumor suppressor genes during mammary tumorigenesis is an aberrant event that can… 
2006
2006
The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin.
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