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cystathionine gamma-lyase activity

Known as: L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming) 
Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+. [RHEA:24918]
National Institutes of Health

Related topics

Related topics

2 relations
CTH geneCysteine Desulfhydrase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Soy protein diet prevents hypermethioninemia caused by portacaval shunt in rats.
In hepatic disorders, abnormal plasma amino acid profiles are observed. In this study, we examined whether soy protein isolate… Expand
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2002
2002
Biosynthesis of sulfur-containing amino acids in Streptomyces venezuelae ISP5230: roles for cystathionine beta-synthase and transsulfuration.
A 0.5 kb fragment of Streptomyces venezuelae ISP5230 genomic DNA was amplified by PCR using primers based on consensus sequences… Expand
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Highly Cited
2001
Highly Cited
2001
Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes.
Rat hepatocytes cultured for 3 days in basal medium expressed low levels of cysteine dioxygenase (CDO) and high levels of gamma… Expand
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1995
1995
Elevation of cystathionine gamma-lyase activity in the serum of rats treated with a single dose of carbon tetrachloride.
Cystathionine gamma-lyase activity in the sera of rats subjected to experimental hepatotoxicity after intraperitoneal… Expand
1993
1993
Changes in cystathionine gamma-lyase levels in rat liver during lactation.
Rat liver cystathionine gamma-lyase activity increased rapidly with the onset of lactation, reaching a maximum value at week 2… Expand
1993
1993
Cloning and bacterial expression of the CYS3 gene encoding cystathionine gamma-lyase of Saccharomyces cerevisiae and the physicochemical and enzymatic properties of the protein
By screening a yeast genomic library, we isolated and characterized a gene rescuing the cysteine requirement in a "cys1" strain… Expand
Highly Cited
1992
Highly Cited
1992
Genetic analysis of a new mutation conferring cysteine auxotrophy in Saccharomyces cerevisiae: updating of the sulfur metabolism pathway.
We have identified a mutation in a gene of Saccharomyces cerevisiae, STR1, that leads to a strict nutritional requirement for… Expand
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1992
1992
Cloning and characterization of the CYS3 (CYI1) gene of Saccharomyces cerevisiae
A DNA fragment containing the Saccharomyces cerevisiae CYS3 (CYI1) gene was cloned. The clone had a single open reading frame of… Expand
1987
1987
Effect of dietary glycine on methionine metabolism in rats fed a high-methionine diet.
The alleviation mechanism of methionine toxicity by dietary glycine was investigated in weanling rats fed a high-methionine diet… Expand
1981
1981
Cystathionine gamma-lyase activity in the cephamycin C producer Streptomyces lactamdurans.
Extracts of the cephamycin C producer S. lactamdurans were found to possess cystathionine gamma-lyase activity (E.C. 4.4.1.1… Expand
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