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Cysteine Desulfhydrase

Known as: Cystine Desulfhydrase, Cystathionine gamma-Lyase [Chemical/Ingredient], gamma-Lyase, Cystathionine 
A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield… 
National Institutes of Health

Related topics

Related topics

14 relations
CTH geneCarbon-Sulfur LyasesIn BloodProcess of secretion

Narrower (4)

CYS3 protein, S cerevisiaeCystathionase DeficiencyMalY protein, E colicystalysin

Papers overview

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1997
1997
Sensitivity to radiation treatment and changes in metallothionein synthesis in a transplanted murine tumor.
A protective role for metallothionein (MT) in cellular injury caused by ionizing radiation has been proposed. To elucidate the… 
1982
1982
Identification of the active-site residue of gamma-cystathionase labeled by the suicide inactivator beta, beta, beta-trifluoroalanine.
Inactivation of gamma-cystathionase by beta, beta, beta-trifluoroalanine, a suicide inactivator of the enzyme, results in… 
Highly Cited
1973
Highly Cited
1973
beta-Cystathionase In Vivo Inactivation by Rhizobitoxine and Role of the Enzyme in Methionine Biosynthesis in Corn Seedlings.
Rhizobitoxine has previously been shown to inactivate irreversibly beta-cystathionase isolated from spinach. In the present… 
1971
1971
The thiol groups of rat liver cystathionase. Influence of pyridoxal phosphate, L-homoserine and L-alanine on the effect of p-chloromercuribenzoate and 5,5-dithiobis-(2-nitrobenzoate) on the enzyme.
Rat liver cystathionase (homoserine hydrolyase) catalyzes the deamination of homoserine and the desulfhydration of cysteine. A… 
1970
1970
Dominance of the wild-type alleles of methionine regulatory genes in Salmonella typhimurium.
SUMMARY elements carrying wild-type alleles of the methionine regulatory genes metJ and K have been transferred from Escherichia… 
1968
1968
Cystathioninuria not associated with vitamin B6 dependency: a probably new type of cystathioninuria.
An infantile case of cystathioninuria was described. The patient had retarded development and marked cystathioninuria. Large… 
1966
1966
Deficiencies of cystathionase and homoserine dehydratase activities in cystathioninuria.
17 Georgiev, G. P., 0. P. Samarina, M. I. Lerman, M. N. Smirnov, and A. N. Severtzov, Nature, 200, 1291 (1963). 8Greenman, D. L… 
1965
1965
Effects of Pyridoxine Deficiency on the Adaptation of Rat Liver Cystathionase to DL-Ethionine and to Thyroidectomy
THE activity of liver cystathionase (‘soluble’ cysteine desulphydrase) of rats is adaptively increased both after thyroidectomy1… 
1964
1964
REPRESSION BY METHIONINE OF CYSTATHIONASE FORMATION IN ESCHERICHIA COLI.
Cystathionase catalyses the formation of homocysteine from cystathionine; its formation in cultures of Escherichia coli is… 
Highly Cited
1962
Highly Cited
1962
The site of binding of pyridoxal-5'-phosphate to heart glutamic-aspartic transaminase.
Pyridoxal-5'-phosphate (PLP) plays a central role as a cofactor of many enzymes of amino acid metabolism. In addition, the…