Antigen-presenting cells control T cell proliferation by regulating amino acid availability.

@article{Edinger2002AntigenpresentingCC,
  title={Antigen-presenting cells control T cell proliferation by regulating amino acid availability.},
  author={Aimee L Edinger and Craig B Thompson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 3},
  pages={1107-9}
}
A ll cells depend on nutrients acquired from the extracellular environment to support the biochemical processes required for cell growth. Although unicellular organisms such as bacteria and yeast have developed strategies to survive nutrient limitation, the growth of these organisms is constrained by nutrient availability. In contrast, mammalian cells exist in a nutrient-rich environment where cell growth is not limited by substrate availability, but rather by the levels of extrinsic growth… CONTINUE READING