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cystathionine beta-synthase activity

Known as: serine sulfhydrase activity, methylcysteine synthase activity, beta-thionase activity 
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O. [EC:4.2.1.22]
National Institutes of Health

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Cystathionine beta-Synthasenegative regulation of cystathionine beta-synthase activity

Papers overview

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Highly Cited
2006
Highly Cited
2006
Suppression of Methionine-Induced Hyperhomocysteinemia by Glycine and Serine in Rats
The hyperhomocysteinemia induced by a dietary addition of 1% methionine was significantly suppressed by the concurrent addition… 
2005
2005
Inhibitory effect of copper on cystathionine beta-synthase activity: protective effect of an analog of the human albumin N-terminus.
Copper was added to truncated, recombinant cystathionine beta-synthase (CBS), and the enzyme activity was assessed by measuring… 
2004
2004
The essentiality of sulfur is closely related to nitrogen metabolism: a clue to hyperhomocysteinaemia
Abstract N and S metabolisms are closely interwoven throughout both the plant and animal kingdoms. The essentiality of S relates… 
1996
1996
The effect of a high-protein diet on cystathionine beta-synthase activity and its transcript levels in rat liver.
Hepatic cystathionine beta-synthase activity was increased in rats fed a high-protein diet for three or five days as compared to… 
1995
1995
Effect of cysteine on expression of cystathionine beta-synthase in the rat liver.
Hepatic cystathionine beta-synthase activity is decreased by the addition of cysteine to the diet. This effect of cysteine was… 
Highly Cited
1991
Highly Cited
1991
Regulation of Sulfate Assimilation by Light and O-Acetyl-l-Serine in Lemna minor L.
The effect of 0.5 millimolar O-acetyl-l-serine added to the nutrient solution on sulfate assimilation of Lemna minor L… 
1989
1989
Effect of vitamin B12-deficiency on the activity of hepatic cystathionine beta-synthase in rats.
The effect of vitamin B12(B12)-deficiency on the activities of hepatic methionine synthase, homocysteine methyltransferase, and… 
1984
1984
Effect of D,L-propargylglycine on cystathionine metabolism in rats.
Hepatic gamma-cystathionase activity at 12 h after the intraperitoneal injection decreased in proportion to the amount of D,L… 
1977
1977
Sulfur metabolism of a mutant of Cephalosporium acremonium with enhanced potential to utilize sulfate for cephalosporin C production.
Characteristics of a mutant of Cephalosporium acremonium with enhanced potential to utilize sulfate for cephalosporin C… 
1977
1977
Effect of trypsin, S-adenosylmethionine and ethionine on L-serine sulfhydrase activity
Trypsin causes an activation of serine sulfhydrase in the liver extracts from intact animals, but inhibits enzyme activity in the… 
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