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cystathionine beta-synthase activity

Known as: serine sulfhydrase activity, methylcysteine synthase activity, beta-thionase activity 
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O. [EC:4.2.1.22]
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
The hyperhomocysteinemia induced by a dietary addition of 1% methionine was significantly suppressed by the concurrent addition… 
2004
2004
Abstract N and S metabolisms are closely interwoven throughout both the plant and animal kingdoms. The essentiality of S relates… 
Highly Cited
1998
Highly Cited
1998
Human cystathionine β-synthase catalyzes the first step in the catabolic removal of the toxic metabolite, homocysteine. It is… 
Highly Cited
1994
Highly Cited
1994
In a recent hypothesis [Selhub and Miller (1992) Am. J. Clin. Nutr. 55, 131-138], we proposed that homocysteinaemia arises from… 
Highly Cited
1993
Highly Cited
1993
Mild homocysteinemia occurs surprisingly often in patients with premature vascular disease. We studied the possible enzymatic… 
Highly Cited
1991
Highly Cited
1991
The effect of 0.5 millimolar O-acetyl-l-serine added to the nutrient solution on sulfate assimilation of Lemna minor L… 
1980
1980
Previous attempts to correlate in vivo pyridoxine-responsiveness with in vitro assays of cystathionine beta-synthase activity in… 
Highly Cited
1978
Highly Cited
1978
We have compared in vivo pyridoxine responsiveness with in vitro cystathionine beta-synthase activity in extracts of confluent… 
Highly Cited
1972
Highly Cited
1972
In higher plants the biosynthesis of l-cysteine from l-serine, acetylCoA, and sulfide requires serine transacetylase and O…