cyclothiazide

Known as: 6-chloro-3,4-dihydro-3-(5-Norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-3,4-dihydro-3-(2-Norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-3-(2-Norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide 
A benzothiadiazide belonging to the class of thiazide diuretics. Cyclothiazide is indicated as adjunctive therapy in edema and in the treatment of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2017
010203019622017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Cyclothiazide (CTZ), a positive allosteric modulator of ionotropic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
AMPA receptor GluRA subunits with mutations at position 750, a residue shown previously to control allosteric regulation by… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The contribution of intersynaptic transmitter diffusion to the AMPA receptor EPSC time course was studied in cultured CA1… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1995
1995
We examined the actions of cyclothiazide, aniracetam, and 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Agonist responses for flip splice variants of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
In whole-cell recordings from mammalian CNS neurons, AMPA-preferring glutamate receptors exhibit strong desensitization in… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 6
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Potentiation by cyclothiazide of recombinant glutamate receptor responses in Xenopus oocytes showed absolute selectivity for AMPA… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
We have investigated the role of AMPA receptor desensitization during transmission at a calyceal synapse. Cyclothiazide blocked… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
A distinctive characteristic of the AMPA subset of glutamate receptor channels is their remarkably rapid desensitization. A… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Concanavalin A, cyclothiazide, and aniracetam, ligands that modulate desensitization at glutamate receptors, were tested for… (More)
Is this relevant?