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Benzothiadiazines

Known as: Benzothiadiazines [Chemical/Ingredient] 
Heterocyclic compounds of a ring with SULFUR and two NITROGEN atoms fused to a BENZENE ring. Members inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and… 
National Institutes of Health

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1,3,2,4-benzodithiadiazineA 837093BPDZ 154DU 717
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.
The synthesis of diversely substituted 3-isopropoxy-, 3-isopropylsulfanyl-, 3-isopropylsulfinyl-, and 3-isobutyl-4H-1,2,4… 
2010
2010
Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer.
Benzothiadiazines differently substituted at the sulfonamidic nitrogen atom, at the stereogenic carbon atom and at the anilinic… 
2009
2009
Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.
The hepatitis C virus (HCV) NS5B polymerase is essential for viral replication and has been a prime target for drug discovery… 
1985
1985
Enantiomers of benzothiadiazine diuretics by direct chromatographic resolution of the racemic drugs.
A number of racemic benzothiadiazine diuretics and two carbonyl analogue drugs were resolved into their optical isomers by liquid… 
1982
1982
Application of conventional (DC) and differential pulse polarography (DPP) to the quality control of benzothiadiazines in tablets. Simultaneous determination of hydrochlorothiazide and dihydralazine…
A previous study of the polarographic behaviour of 14 benzothiadiazines having diuretic properties enabled possible reaction… 
Review
1964
Review
1964
Clinical and Physiological Implications of Diabetes Induced by Benzothiadiazines
Chlorothiazide, the first of the diuretic and antihypertensive benzothiadiazines, was introduced into medical practice in 1958… 
Highly Cited
1963
Highly Cited
1963
Drug-Induced Diabetes: Diabetogenic Activity of Long-Term Administration of Benzothiadiazines
During the course of studies of hypertensive patients, including a double blind study, observations were made concerning the… 
1962
1962
Studies of N-dealkylation of some aromatic sulfonamides.
Highly Cited
1960
Highly Cited
1960
EFFECTS OF BENZOTHIADIAZINES ON SERUM AND TOTAL BODY ELECTROLYTES *
1960
1960
ANIMAL PHARMACOLOGY OF THE NEW DIURETICS: BENZOTHIADIAZINES, SPIROLACTONES, AND PHTHALIMIDINES
The history of the search for the benzothiadiazines gives some insight into the mechanism of diuretic action that they exhibit… 
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