Skip to search formSkip to main contentSkip to account menu

cyclothialidine

Known as: L-Alanine, N-(S-((2-carboxy-4,6-dihydroxy-3-methylphenyl)methyl)-N-(N-(cis-3-hydroxy-1-L-seryl-L-prolyl)-L-seryl)-L-cysteinyl)-, kappa-lactone 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Cyclic PeptidesTopoisomerase II Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Molecular modelling assisted design and synthesis of cyclothialidine derivatives as DNA gyrase inhibitors
Since cyclothialidine was discovered as the most active DNA gyrase inhibitor in 1994, enormous efforts have been devoted to make… 
2002
2002
A scintillation proximity assay amenable for screening and characterization of DNA gyrase B subunit inhibitors.
DNA gyrase is the target of coumarin and cyclothialidine antibacterials, which bind to the B subunit of the enzyme (GyrB… 
1999
1999
Design, synthesis and evaluation of cyclothialidine analogues as DNA gyrase inhibitors
Cyclothialidine, a natural product isolated from Streptomyces .filipinensis NR0484, has been proven to be a potent and selective… 
1997
1997
Cyclothialidine analogs, novel DNA gyrase inhibitors.
DNA gyrase inhibitors, cyclothialidines B, C, D and E were isolated from four Streptomycete strains (NR 0659, NR 0660, NR 0661… 
1995
1995
Characterization of the Binding Site for Cyclothialidine on the B Subunit of DNA Gyrase (*)
The mechanism of inhibition of DNA gyrase by cyclothialidine, a novel gyrase inhibitor isolated from Streptomyces filipinensis… 
1994
1994
Cyclothialidine, a novel DNA gyrase inhibitor. I. Screening, taxonomy, fermentation and biological activity.
Streptomyces filipinensis NR 0484 produced a new DNA gyrase inhibitor, cyclothialidine. It showed potent activity against DNA… 
1994
1994
Cyclothialidine, a novel DNA gyrase inhibitor. II. Isolation, characterization and structure elucidation.
Cyclothialidine is a novel DNA gyrase inhibitor produced by Streptomyces filipinensis NR 0484. It was isolated from the culture… 
Highly Cited
1993
Highly Cited
1993
Biological characterization of cyclothialidine, a new DNA gyrase inhibitor
Cyclothialidine is a new DNA gyrase inhibitor isolated from Streptomyces filipinensis NR0484. Structurally, it belongs to a new… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)