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cyclopropapyrroloindole

Known as: CPI, cyclopropapyrroloindole (CPI) 
National Institutes of Health

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2 relations

Broader (2)

CyclopropanesIndoles

Papers overview

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2017
2017
Renal Toxicity Related to Immune Checkpoint Inhibitors
As early as the 18th century, physicians noticed that some cancer patients went into remission after developing fevers from… 
2016
2016
Outcomes After Pediatric Out-of-Hospital Cardiopulmonary Interventions
Objective The aim of the study was to evaluate outcomes after pediatric out-of-hospital cardiopulmonary interventions (CPIs) by… 
2016
2016
Impact pronostique des mesures tomodensitométriques dans la fibrose pulmonaire idiopathique
2011
2011
Manipulative interplay of two adozelesin molecules with d(ATTAAT)₂achieving ligand-stacked Watson-Crick and Hoogsteen base-paired duplex adducts.
Previous structural studies of the cyclopropapyrroloindole (CPI) antitumor antibiotics have shown that these ligands bind… 
2005
2005
Specific adenine alkylation by pyrrole-imidazole CBI conjugates.
We examined DNA alkylation by pyrrole (Py)-imidazole (Im) hairpin polyamides, which possess 1,2,9,9a-tetrahydrocyclopropa[1,2-c… 
2004
2004
Enantioselective DNA alkylation by a pyrrole-imidazole S-CBI conjugate.
Conjugates 12S and 12R of N-methylpyrrole (Py)-N-methylimidazole (Im) seven-ringed hairpin polyamide with both enantiomers of 1,2… 
2000
2000
Determination of the structural role of the linking moieties in the DNA binding of adozelesin.
Adozelesin (formerly U73975, The Upjohn Co.) is a monofunctional DNA alkylating analogue of the antitumor antibiotic (+)-CC-1065… 
1999
1999
Some of the issues are supplemented with summaries of data from other sources or augmented with data not reported in the Daily. (Short Term Expectations, CPI, Labour Force, etc.)
1996
1996
Rapid and efficient hybridization-triggered crosslinking within a DNA duplex by an oligodeoxyribonucleotide bearing a conjugated cyclopropapyrroloindole.
The antitumor antibiotic CC-1065 binds in the minor groove of double-stranded DNA, and the cyclopropapyrroloindole (CPI) subunit… 
1993
1993
Sequence-selective guanine reactivity by duocarmycin A.
High selectivity for covalent reaction at adenine N-3 within duplex DNA is a distinguishing feature of the CC-1065 and… 
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