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cycloplatam

Known as: ammine(cyclopentylamino)malatoplatinum(II), cycloplatin 
National Institutes of Health

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Organoplatinum Compounds

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2006
2006
Cytogenetic toxicity of cycloplatam in human lymphocytes: detection by the micronucleus test and fluorescence in situ hybridization
Cycloplatam has been shown to be effective in the treatment of pleural mesothelioma, myeloma and ovarian carcinoma. Cycloplatam… 
2003
2003
Genotoxic Action of Cycloplatam, a New Platinum Antitumor Drug, on Mammalian Cells in vivo and in vitro
Cycloplatam (CP), a new antitumor platinum compound of the second generation, was first synthesized in Russia. This drug shows… 
2001
2001
Changes in microtubules and microfilaments due to a combined effect of ultrasound and cytostatics in HeLa cells.
Treatment of HeLa cells with low intensity ultrasound and two cytostatic drugs, cycloplatin and methotrexate, resulted in a… 
2001
2001
Results of phase II clinical trial of cycloplatam in refractory solid tumors
Cycloplatam, a new platinum derivative, evolved at N.S. Kurnakov Institute of General and Inorganic Chemistry in 1982, has been… 
1996
1996
[Effect of anti-tumor agents cisplatin and cycloplatam on membrane protein kinase C activity in murine T-lymphocytes].
: The effect of cisplatin and the new drug cycloplatam (amine (cyclopentylamine)-S-(-)-malatoplatinum (II)) on protein kinase C… 
1996
1996
[Cycloplatam in the treatment of patients with disseminated prostatic cancer].
A 22% response rate was achieved in clinical trials of Russian drug cycloplatam in disseminated and hormone-resistant cancer of… 
1995
1995
[Biochemical mechanisms of resistance to a new antineoplastic agent amin(cyclopeptidylamin)-S-(-)-malatoplatinum (II) (cycloplatam)].
: The "in vivo" effect of cycloplatam on DNA synthesis in leukemia P388/o (parent strain), P388/c (cycloplatam-resistant strain… 
1989
1989
Action of cisplatin and cycloplatam on the rat kidney
On the 5th day after intraperitoneal injection of cisplatin the rats developed renal insufficiency. The concentration of… 
1988
1988
Cycloplatam and oxoplatin--the new antitumor platinum compounds of the second generation.
Cycloplatam, ammine(cyclopentylamino)-S-(-)-malatoplatinum(II), and oxoplatin, cis-dichloro-diammine-trans-dihydroxoplatinum(IV… 
1988
1988
Cycloplatam and oxoplatin--the new antitumor platinum compounds of the second generation.
Cycloplatam, ammine(cyclopentylamino)-S-(-)-malatoplatinum(II), and oxoplatin, cis-dichloro-diammine-trans-dihydroxoplatinum(IV… 
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