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cyclic AMP-regulated phosphoprotein ARPP-21

Known as: ARPP-21, Thymocyte cAMP-Regulated Phosphoprotein, cAMP-Regulated Phosphoprotein 21 
cAMP-regulated phosphoprotein 21 (812 aa, ~ 89 kDa) is encoded by the human ARPP21 gene. This protein may play a role in cellular signaling.
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

ARPP-21B
ARPP21 geneSignal TransductionSignaling Pathway Gene

Broader (1)

Phosphoproteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
ARPP-21 is a cyclic AMP-regulated phosphoprotein of M(r) 21 kDa that is enriched in the cell bodies and terminals of medium-sized… Expand
Highly Cited
1999
Highly Cited
1999
Expression of the Striatal DARPP-32/ARPP-21 Phenotype in GABAergic Neurons Requires Neurotrophins In Vivo andIn Vitro
The medium spiny neuron (MSN) is the major output neuron of the caudate nucleus and uses GABA as its primary neurotransmitter. A… Expand
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1998
1998
Basal ganglia precursors found in aggregates following embryonic transplantation adopt a striatal phenotype in heterotopic locations.
Transplantation of immature CNS-derived cells into the developing brain is a powerful approach to investigate the factors that… Expand
Highly Cited
1994
Highly Cited
1994
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue
In this study we have isolated and sequenced human cDNAs for the phosphoproteins DARPP-32, ARPP-21, and ARPP-16/19, and have… Expand
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Highly Cited
1989
Highly Cited
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. II. Immunocytochemical localization in rat brain
ARPP-21, a cAMP-regulated phosphoprotein, has been studied by immunocytochemistry to determine its cellular and regional… Expand
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Highly Cited
1989
Highly Cited
1989
Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy.
This study was undertaken to evaluate the levels of cAMP-regulated phosphoproteins in the striatum of patients with… Expand
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1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic…
ARPP-21 (cyclic AMP-regulated phosphoprotein, Mr = 21,000) is a cytosolic neuronal phosphoprotein that is highly enriched in… Expand
1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. II. Molecular cloning and nucleotide sequence
A cDNA clone for the mRNA of bovine ARPP-21 (cAMP-regulated phosphoprotein, Mr = 21,000 as determined by SDS-PAGE) was isolated… Expand
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1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus
ARPP-21 (cAMP-regulated phosphoprotein, Mr = 21,000 as determined by SDS/PAGE) is a major cytosolic substrate for cAMP-stimulated… Expand
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1988
1988
Regulation by cAMP and vasoactive intestinal peptide of phosphorylation of specific proteins in striatal cells in culture.
We have studied three low molecular weight phosphoproteins, ARPP-16, ARPP-19, and ARPP-21 (cAMP-regulated phosphoproteins of Mr… Expand
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