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cyclic AMP-regulated phosphoprotein ARPP-21

Known as: ARPP-21, Thymocyte cAMP-Regulated Phosphoprotein, cAMP-Regulated Phosphoprotein 21 
cAMP-regulated phosphoprotein 21 (812 aa, ~ 89 kDa) is encoded by the human ARPP21 gene. This protein may play a role in cellular signaling.
National Institutes of Health

Related topics

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5 relations

Narrower (1)

ARPP-21B
ARPP21 geneSignal TransductionSignaling Pathway Gene

Broader (1)

Phosphoproteins

Papers overview

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2016
2016
Role of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine Integration
In reward learning, the integration of NMDA-dependent calcium and dopamine by striatal projection neurons leads to potentiation… Expand
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2000
2000
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
ARPP-21 is a cyclic AMP-regulated phosphoprotein of M(r) 21 kDa that is enriched in the cell bodies and terminals of medium-sized… Expand
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Highly Cited
1999
Highly Cited
1999
Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro.
The medium spiny neuron (MSN) is the major output neuron of the caudate nucleus and uses GABA as its primary neurotransmitter. A… Expand
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1994
1994
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue.
In this study we have isolated and sequenced human cDNAs for the phosphoproteins DARPP-32, ARPP-21, and ARPP-16/19, and have… Expand
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1993
1993
Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra.
ARPP-21 is a cyclic AMP-regulated phosphoprotein (M(r) = 21,000) that has a distribution in brain similar to that of DARPP-32… Expand
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1990
1990
ARPP-21, A cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: Tissue distribution and regulation of phosphorylation in rat brain
ARPP-21 (cAMP-regulated phosphoprotein, Mr = 21,000 as determined by polyacrylamide gel electrophoresis in the presence of sodium… Expand
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1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
ARPP-21, a cAMP-regulated phosphoprotein, has been studied by immunocytochemistry to determine its cellular and regional… Expand
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1989
1989
Striatal phosphoproteins in Parkinson disease and progressive supranuclear palsy.
This study was undertaken to evaluate the levels of cAMP-regulated phosphoproteins in the striatum of patients with… Expand
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1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
ARPP-21 (cAMP-regulated phosphoprotein, Mr = 21,000 as determined by SDS/PAGE) is a major cytosolic substrate for cAMP-stimulated… Expand
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1989
1989
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic…
ARPP-21 (cyclic AMP-regulated phosphoprotein, Mr = 21,000) is a cytosolic neuronal phosphoprotein that is highly enriched in… Expand
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