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custirsen

 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
BACKGROUND Clusterin is a chaperone protein associated with treatment resistance and upregulated by apoptotic stressors such as… Expand
2017
2017
BACKGROUND Docetaxel and cabazitaxel improve overall survival compared with mitoxantrone in patients with metastatic castration… Expand
2017
2017
AIMS Custirsen (OGX-011/TV-1011), a second-generation antisense oligonucleotide that reduces clusterin production, is under… Expand
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2015
2015
5009 Background: Clusterin is a chaperone protein associated with treatment resistance and upregulated by apoptotic stressors… Expand
2015
2015
AIMS Custirsen (OGX-011/TV-1011), a second-generation antisense oligonucleotide (ASO) that reduces clusterin production, is under… Expand
2013
2013
Elevated levels of clusterin (CLU), a stress‐induced and secreted cytoprotective chaperone, are associated with advanced tumor… Expand
Highly Cited
2012
Highly Cited
2012
Purpose: Clusterin (CLU), an antiapoptotic, stress-associated protein, confers resistance to therapy when overexpressed. This… Expand
Highly Cited
2011
Highly Cited
2011
Purpose: Clusterin (CLU) is an antiapoptotic, stress-induced protein conferring treatment resistance when overexpressed. This… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
2011
2011
TPS180 Background: Custirsen (OGX-011) is a second generation antisense oligonucleotide (ASO) with a prolonged tissue half-life… Expand
2008
2008
5002 Background: There is no standard of care when pts with metastatic HRPC manifest disease progression (PD) after 1st-line… Expand