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cullin-3

Known as: CUL3, Cullin Homolog 3, CUL-3 
Cullin-3 (768 aa, ~89 kDa) is encoded by the human CUL3 gene. This protein plays a role in protein ubiquitination and cell cycle arrest.
National Institutes of Health

Related topics

Related topics

9 relations
CUL3 geneCanonical Wnt Signaling PathwayCullin Family ProteinGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics.
2017
2017
OsCUL 3 a Negatively Regulates Cell Death and Immunity by Degrading OsNPR 1 in Rice
Qunen Liu,a,b,c,1 Yuese Ning,b,1 Yingxin Zhang,a,c,1 Ning Yu,a,c Chunde Zhao,a,c Xiaodeng Zhan,a,c Weixun Wu,a,c Daibo Chen,a,c… 
2015
2015
Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor
Non–small cell lung cancers (NSCLC) harbor thousands of passenger events that hide genetic drivers. Even highly recurrent events… 
2015
2015
Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data
BackgroundMolecular signaling of angiogenesis begins within hours after initiation of a stroke and the following regulation of… 
2013
2013
An emerging role for Cullin-3 mediated ubiquitination in sleep and circadian rhythm
Although the neurophysiological correlates of sleep have been thoroughly described, genetic mechanisms that control sleep… 
Highly Cited
2012
Highly Cited
2012
CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock
Eukaryotic circadian clocks rely on transcriptional feedback loops. In Drosophila, the PERIOD (PER) and TIMELESS (TIM) proteins… 
2012
2012
Cullin-3 and the endocytic system
Cullin-RING-ligases (CRLs) comprise the largest class of multisubunit E3 ubiquitin ligases, which regulate a broad range of… 
2010
2010
Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3-RINGBox1 protein complex and elucidation of its quaternary structure with Keap1.
2004
2004
Molecular and functional characterization of Arabidopsis Cullin 3 A
Monika Dieterle, Alexis Thomann, Jean-Pierre Renou, Yves Parmentier, Valerie Cognat, Gaetan Lemonnier, Rebecca Müller, Wen-Hui… 
2004
2004
Cellular stress-related protein expression in Helicobacter pylori-infected gastric epithelial AGS cells.
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