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cucurbitacin I

Known as: elatericin B 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

JSI 124

Broader (1)

Triterpenes

Papers overview

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2017
2017
Inhibition of Telomerase Activity by Cucurbitacin I in Colon Cancer Cell Line, LS174T
Telomerase activity is dependent on the expression level of human telomerase reverse transcriptase (hTERT) in cancer cells. hTERT… 
2017
2017
[Cucurbitacin I (JSI-124)-induced apoptosis of HepG2 cells via p53 signaling pathway].
Objective To study the mechanism underlying cucurbitacin I (JSI-124) inducing cell apoptosis in human hepatoma HepG2 cells… 
2017
2017
JSI-124 inhibits IgE production in an IgE B cell line.
2016
2016
[Role of CXCR4/STAT3 in mesenchymal stromal cell-mediated drug resistance of acute leukemia cells].
OBJECTIVE To explore the role of CXCR4/STAT3 in mesenchymal stromal cell (MSC)-mediated drug resistance of AML cells. METHODS… 
2015
2015
Combination of immunoprecipitation (IP)-ATP_Glo kinase assay and melanogenesis for the assessment of potent and safe PAK1-blockers in cell culture.
Cucurbitacin I (CBI) is a triterpene from a bitter melon called Goya grown in Okinawa, Japan, and directly inhibits both the Tyr… 
2015
2015
Role of JAK2/STAT3 pathway in vascular function of pulmonary fibrosis patients
Background: Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive lung disease with a life expectancy of 2-5 years. A… 
2013
2013
Cucurbitacin I Inhibits Rac 1 Activation in Breast Cancer Cells by a Reactive Oxygen Species-Mediated Mechanism and Independently of Janus Tyrosine Kinase 2 and P-Rex 1 s
The small GTPase Rac1 has been widely implicated in mammary tumorigenesis and metastasis. Previous studies established that… 
2011
2011
Abstract 490: Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in non-small cell lung cancer-derived CD133+ cells
Background: STAT3 signaling is reported to promote tumor malignancy and recurrence in non-small cell lung cancer (NSCLC). The… 
2008
2008
Development of a STAT3 reporter prostate cancer cell line for high throughput screening of STAT3 activators and inhibitors.
2006
2006
STAT3-independent inhibition of lysophosphatidic acid-mediated upregulation of connective tissue growth factor (CTGF) by cucurbitacin I.
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