cremophor EL

Known as: cremophore EL 
 
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Genexol-PM is a novel Cremophor EL (CrEL)-free polymeric micelle formulation of paclitaxel (Taxol). This multicenter… (More)
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2002
2002
It has been hypothesized that the paclitaxel vehicle Cremophor EL (CrEL) is responsible for nonlinear drug disposition by… (More)
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Review
2001
Review
2001
Cremophor EL (CrEL) is a formulation vehicle used for various poorly-water soluble drugs, including the anticancer agent… (More)
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Highly Cited
2001
Highly Cited
2001
Nonlinear disposition of paclitaxel (Taxol) in cancer patients has been described in several studies, but the underlying… (More)
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Highly Cited
1999
Highly Cited
1999
We have determined the in vitro and in vivo cellular distribution of the antineoplastic agent paclitaxel (Taxol) in human blood… (More)
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Highly Cited
1999
Highly Cited
1999
SummaryThe non-linear plasma pharmacokinetics of paclitaxel in patients has been well established, however, the exact underlying… (More)
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Highly Cited
1996
Highly Cited
1996
Studies in humans and mice have demonstrated a nonlinear pharmacokinetic behavior of paclitaxel. Because of its poor water… (More)
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1994
1994
Cremophor EL (CRM) is a non-ionic amphipathic emulsifier which has been used as a parenteral vehicle for many hydrophobic drugs… (More)
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1991
1991
1. Interaction of cremophor EL (CRM) with human plasma lipoproteins and nonlipoproteins has been investigated by… (More)
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Highly Cited
1990
Highly Cited
1990
A polyethoxylated castor oil, Cremophor EL, which is used as a vehicle for p.o. and i.v. administration of water-insoluble… (More)
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