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cremophor EL

Known as: cremophore EL 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
  • D-W. Kim, S. Kim, +6 authors D. Heo
  • Annals of oncology : official journal of the…
  • 2007
  • Corpus ID: 25460407
BACKGROUND Genexol-PM is a novel Cremophor EL (CrEL)-free polymeric micelle formulation of paclitaxel (Taxol). This multicenter… Expand
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Review
2003
Review
2003
The non-ionic surfactants Cremophor® EL (CrEL; polyoxyethyleneglycerol triricinoleate 35) and polysorbate 80 (Tween® 80; polyoxy… Expand
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Highly Cited
2002
Highly Cited
2002
It has been hypothesized that the paclitaxel vehicle Cremophor EL (CrEL) is responsible for nonlinear drug disposition by… Expand
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Review
2001
Review
2001
Cremophor EL (CrEL) is a formulation vehicle used for various poorly-water soluble drugs, including the anticancer agent… Expand
Highly Cited
1999
Highly Cited
1999
We have determined the in vitro and in vivo cellular distribution of the antineoplastic agent paclitaxel (Taxol) in human blood… Expand
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Highly Cited
1999
Highly Cited
1999
SummaryThe non-linear plasma pharmacokinetics of paclitaxel in patients has been well established, however, the exact underlying… Expand
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Highly Cited
1997
Highly Cited
1997
PURPOSE We performed a pharmacologic investigation of paclitaxel (PTX) infused over 3 hours and bolus doxorubicin (DOX) to assess… Expand
Highly Cited
1996
Highly Cited
1996
Studies in humans and mice have demonstrated a nonlinear pharmacokinetic behavior of paclitaxel. Because of its poor water… Expand
Highly Cited
1991
Highly Cited
1991
1. Interaction of cremophor EL (CRM) with human plasma lipoproteins and nonlipoproteins has been investigated by… Expand
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Highly Cited
1990
Highly Cited
1990
A polyethoxylated castor oil, Cremophor EL, which is used as a vehicle for p.o. and i.v. administration of water-insoluble… Expand