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coumestan

Known as: Benzofurocoumarin 
An estrogen-like substance (phytoestrogen) made by some plants. Coumestans may have anticancer effects.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
A concise and efficient approach to the syntheses of coumestan analogues has been developed. The underpinning strategy involves a… Expand
Highly Cited
2008
Highly Cited
2008
The hepatitis C virus (HCV) NS5B is essential for viral RNA replication and is therefore a prime target for development of HCV… Expand
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2008
2008
Two 2-phenylbenzofurans, lespedezavirgatol (1) and lespedezavirgatal (2), and a coumestan, lespedezacoumestan (3), were isolated… Expand
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Highly Cited
2006
Highly Cited
2006
Abstract: Phytoestrogens may play a role in hormone-related diseases such as cancer, but epidemiological and clinical data are… Expand
Highly Cited
2005
Highly Cited
2005
[reaction: see text] The iodocyclization of acetoxy-containing 2-(1-alkynyl)anisoles and subsequent direct palladium-catalyzed… Expand
Highly Cited
2005
Highly Cited
2005
Here, we examined phytoestrogens, isoflavones (genistein, daidzein, glycitein, biochanin A and ipriflavone), flavones (chrysin… Expand
Highly Cited
2004
Highly Cited
2004
AbstractBackground and objective: Phytoestrogens (weak estrogens found in plants or derived from plant precursors by human… Expand
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Highly Cited
2004
Highly Cited
2004
Fruits of Pongamia pinnata afforded four new furanoflavonoids, pongapinnol A-D (1-4), and a new coumestan, pongacoumestan (5… Expand
Highly Cited
2002
Highly Cited
2002
Higher consumption of phytoestrogens might be protective against certain chronic diseases. Accurate quantification of habitual… Expand
2000
2000
  • Kraus, Zhang
  • The Journal of organic chemistry
  • 2000
  • Corpus ID: 40658062
The synthesis of coumestrol has been achieved in five steps from 1, 3-dimethoxybenzene. The key step is a photochemical… Expand